Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10772752 | 0.98 | HSD17B10 (0.52) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| Pyridine SCHEMBL5452272 | 0.83 | CYP19A1 (0.51) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL6924446 | 0.82 | RAB9A (0.46) | HSD17B10LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL18727667 | 0.80 | HSD17B10 (0.58) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL23355573 | 0.78 | HSD17B10 (0.56) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL380364 | 0.78 | HSD17B10 (0.56) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL1467052 | 0.76 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL1467050 | 0.76 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20412354 | 0.76 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL27950381 | 0.76 | HSD17B10 (0.54) | HSD17B10LMNACYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776346-B1 | 1,5-Diphenylpyrazoles | MERCK PATENT GMBH (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-1776346-A1 | 1,5-DIPHENYLPYRAZOLES | Merck Patent GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018082-A1 | 1,5-DIPHENYLPYRAZOLES | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |
| EP-0564409-B1 | Pyrimidin derivatives and process for their preparation | NOVARTIS AG (CH) | 2000-01-19 | — | — | EP | disclosed |
| EP-0564409-A1 | Pyrimidin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-10-06 | — | — | EP | disclosed |
| EP-0330927-A2 | Pyridine-4-carboxylic-acid anilide | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |
| EP-0018533-A1 | Substituted pentane (or pentene) carboxylic acids and their derivatives, process for their preparation and their use for the preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |