Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15161586 | 0.80 | ABCG2 (0.41) | ADORA3ABCG2KDM4EGAAKMT2A | |
| SCHEMBL4629962 | 0.77 | KDM4E (0.38) | NR4A2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL5986734 | 0.77 | KDM4E (0.35) | ADORA3ABCG2NR4A2KDM4EGAA | |
| SCHEMBL4629964 | 0.77 | GAA (0.38) | ADORA3NR4A2KDM4EGAAKMT2A | |
| SCHEMBL5172022 | 0.77 | DDR2 (0.34) | ADORA3ABCG2KDM4EGAAKCNA3 | |
| SCHEMBL15159746 | 0.76 | ABCG2 (0.35) | ADORA3ABCG2KDM4EGAAKCNA3 | |
| SCHEMBL7602386 | 0.75 | ALDH1A1 (0.49) | ADORA3NR4A2KDM4EGAAKMT2A | |
| SCHEMBL5492196 | 0.74 | ADORA3 (0.39) | ADORA3ABCG2NR4A2KDM4EGAA | |
| SCHEMBL2719464 | 0.74 | TDO2 (0.42) | ADORA3NR4A2KDM4EGAAKMT2A | |
| SCHEMBL22356152 | 0.74 | KDM4E (0.44) | ADORA3NR4A2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1785426-A1 | NOVEL CARBAPENEM COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-05-16 | — | — | EP | disclosed |
| US-4933355-A | ALDOSE REDUCTASE INHIBITORS | SANKYO COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0337819-A1 | Thiazole derivatives, their preparation and their use in the treatment of diabetes complications | Sankyo Company Limited (JP) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | C1R, C3AR1, OXA1L | ADORA3 1263/4885ABCG2 2416/4885NR4A2 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.