Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958141 | 1.00 | KEAP1 (0.42) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL10448783 | 1.00 | KEAP1 (0.42) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL8872460 | 0.95 | KEAP1 (0.38) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL11454390 | 0.95 | KEAP1 (0.38) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL11026818 | 0.95 | KEAP1 (0.38) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL749097 | 0.90 | KCNN4 (0.38) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL3502282 | 0.90 | KCNN4 (0.38) | KEAP1NFE2L2CYP2D6KDM4ENPC1 | |
| SCHEMBL27838356 | 0.84 | KEAP1 (0.50) | KEAP1NFE2L2CYP2D6HRH1MEN1 | |
| SCHEMBL5717261 | 0.82 | KEAP1 (0.48) | KEAP1NFE2L2CYP2D6HRH1MEN1 | |
| Bromide SCHEMBL11245316 | 0.80 | KEAP1 (0.47) | KEAP1NFE2L2CYP2D6HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299342-B1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-05-02 | — | — | EP | claimed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | claimed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | claimed |
| WO-2024127999-A1 | METHOD FOR PRODUCING CYCLIC OLEFIN COMPOUND | 三井化学株式会社 | 2024-06-20 | — | — | WO | disclosed |
| EP-1299342-B1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | disclosed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| EP-0811629-B1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL IND LTD (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5880301-A | CATALYSTS FOR PREPARATION OF OPTICALLY ACTIVE BETA-HYDROXYKETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0811629-A1 | OPTICALLY ACTIVE BIDENTATE PHOSPHINE LIGAND/PALLADIUM COMPLEX | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-12-10 | — | — | EP | disclosed |
| EP-0384517-A2 | Copolymers of carbon monoxide | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-08-29 | — | — | EP | disclosed |
| EP-0354845-A1 | Bimetallic bridged platinum hydrides, process for their preparation and their use in catalytic chemical reactions | ELF ATOCHEM S.A. (FR) | 1990-02-14 | — | — | EP | disclosed |
| EP-0083158-B1 | NOVEL ALDEHYDES AND PROCESS FOR PRODUCING THE SAME | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1985-08-07 | — | — | EP | disclosed |
| EP-0083158-A1 | Novel aldehydes and process for producing the same | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1983-07-06 | — | — | EP | disclosed |
| US-4370258-A | PLATINUM CATALYST, INB METAL HALIDE ASSISTANT CATALYST AND BIDENTATE LIGAND PROMOTER | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4358621-A | CATALYTIC HYDROFORMYLATION OF OLEFIN | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1982-11-09 | — | — | US | disclosed |
| EP-0039830-A1 | Process for the preparation of optically active compounds and their use in the preparation of vitamin E | BASF Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| US-4237072-A | HYDROGENATION IN THE PRESENCE OF A RHODIUM CHIRAL PHOSPHINE COMPLEX FORMED IN SITU | RHONE-POULENC INDUSTRIES (FR) | 1980-12-02 | — | — | US | disclosed |
| US-4229381-A | HYDROFORMYLATION OF OLEFINS; PLATINUM CATALYST; BIDENTATE LIGAND | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1980-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | HNMT, CYP1A1, HRH3 | KEAP1 555/4885NFE2L2 385/4885CYP2D6 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.