SCHEMBL517307

SCHEMBL517307

O=C(NC12CC3CC(CC(C3)C1)C2)c1ccc(C2OCC3(CO2)COC(c2ccc(C(=O)NC45CC6CC(CC(C6)C4)C5)cc2)OC3)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.61
POLB P06746 2/20 0.59
FAAH O00519 4/20 0.58
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
PKM P14618 1/20 0.49
TSHR P16473 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
HTT P42858 1/20 0.48
ATM Q13315 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
EPHX1 P07099 1/20 0.46
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28355432 0.76 FAAH (0.78) CNR2POLBFAAHALDH1A1LMNA
SCHEMBL2917775 0.76 CNR2 (1.00) CNR2POLBFAAHALDH1A1LMNA
SCHEMBL11450782 0.75 CNR2 (0.73) CNR2POLBFAAHALDH1A1PKM
SCHEMBL7122051 0.75 POLB (1.00) CNR2POLBFAAHALDH1A1LMNA
SCHEMBL1421026 0.75 FAAH (1.00) CNR2POLBFAAHALDH1A1TSHR
SCHEMBL8178904 0.73 MEN1 (0.60) POLBALDH1A1TSHRMAPTHPGD
SCHEMBL21309851 0.73 CNR2 (0.69) CNR2POLBFAAHALDH1A1LMNA
SCHEMBL21292793 0.73 CNR2 (0.69) CNR2POLBFAAHALDH1A1LMNA
SCHEMBL22308141 0.73 FAAH (0.82) CNR2POLBFAAHALDH1A1PKM
SCHEMBL19736415 0.73 CNR2 (0.76) CNR2POLBFAAHALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2392458-B1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEM CO LTD (JP) 2018-03-14 EP disclosed
US-9023921-B2 Method for inhibiting crystal growth rate of amide compound and method for producing molded article of polyolefin-based resin NEW JAPAN CHEMICAL CO., LTD. (JP) 2015-05-05 US disclosed
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
EP-2431415-A1 METHOD FOR CONTROLLING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN New Japan Chemical Co., Ltd. (JP) 2012-03-21 EP disclosed
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-09 US disclosed
US-20120028006-A1 POLYPROPYLENE RESIN MOLDED ARTICLE NEW JAPAN CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2392458-A2 POLYPROPYLENE RESIN MOLDED ARTICLE New Japan Chemical Co., Ltd. (JP) 2011-12-07 EP disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035304-A1 METHOD FOR INHIBITING CRYSTAL GROWTH RATE OF AMIDE COMPOUND AND METHOD FOR PRODUCING MOLDED ARTICLE OF POLYOLEFIN-BASED RESIN MNAT1, RFT1, RTF1 CNR2 3297/4885POLB 1048/4885FAAH 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.