Benzil

Benzil

SCHEMBL5173236

CCCCCC[C@@H](O)C/C=C\CCCCCCCC(=O)OC(=O)C(O)CO.O=C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.54
FFAR4 Q5NUL3 1/20 0.54
FAAH O00519 5/20 0.48
DGKA P23743 1/20 0.47
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
PRKCA P17252 2/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCD Q05655 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
SOAT2 O75908 1/20 0.40
SOAT1 P35610 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120986 0.89 FFAR1 (0.63) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL15686 0.89 FFAR1 (0.63) FFAR1FFAR4FAAHDGKANFKB1
Propene SCHEMBL22734254 0.85 FFAR1 (0.58) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL5417541 0.85 FFAR1 (0.61) FFAR1FFAR4FAAHDGKANFKB1
Ricinoleic Acid SCHEMBL5421088 0.84 FFAR1 (0.77) FFAR1FFAR4FAAHNFKB1NFKB2
SCHEMBL9462680 0.81 FFAR1 (0.64) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL16045989 0.80 FFAR1 (0.60) FFAR1FFAR4FAAHDGKANFKB1
SCHEMBL15664644 0.80 DGKA (0.66) FAAHDGKATRPV1PRKCAPRKCE
SCHEMBL1768202 0.80 DGKA (0.66) FAAHDGKATRPV1PRKCAPRKCE
SCHEMBL15602 0.80 DGKA (0.66) FAAHDGKATRPV1PRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250159-B1 Compositions comprising at least one ester of at least one hydroxylated aliphatic compound L'ORéAL S.A. (FR) 2007-07-31 US claimed
EP-1097699-B1 Cosmetic composition comprising hydroxylated fatty acid ester OREAL (FR) 2007-05-23 EP claimed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US claimed
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester L'OREAL (FR) 2004-08-26 US claimed
EP-1433458-A1 Cosmetic composition without lanolin and comprising an aromatic ester of hydroxylated acid L'OREAL (FR) 2004-06-30 EP claimed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US claimed
EP-1254649-A1 Cosmetic compositions comprising an ester and a sunscreen L'OREAL (FR) 2002-11-06 EP claimed
EP-1097699-A1 Cosmetic composition comprising hydroxylated fatty acid ester L'OREAL (FR) 2001-05-09 EP claimed
US-7250159-B1 Compositions comprising at least one ester of at least one hydroxylated aliphatic compound L'ORéAL S.A. (FR) 2007-07-31 US disclosed
EP-1097699-B1 Cosmetic composition comprising hydroxylated fatty acid ester OREAL (FR) 2007-05-23 EP disclosed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US disclosed
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester L'OREAL (FR) 2004-08-26 US disclosed
EP-1433458-A1 Cosmetic composition without lanolin and comprising an aromatic ester of hydroxylated acid L'OREAL (FR) 2004-06-30 EP disclosed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US disclosed
EP-1254649-A1 Cosmetic compositions comprising an ester and a sunscreen L'OREAL (FR) 2002-11-06 EP disclosed
EP-1097699-A1 Cosmetic composition comprising hydroxylated fatty acid ester L'OREAL (FR) 2001-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester CYP51A1, ELOVL3, ELOVL5 FFAR1 38/4885FFAR4 29/4885FAAH 28/4885
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group KRT18, CUTA, TYR FFAR1 3456/4885FFAR4 3075/4885FAAH 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.