Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539789 | 1.00 | EPHX1 (0.38) | EPHX1DHODHALDH1A1TP53TSHR | |
| SCHEMBL11145639 | 0.80 | EPHX1 (0.38) | EPHX1ALDH1A1TP53TSHRCA12 | |
| SCHEMBL6592409 | 0.79 | TP53 (0.47) | EPHX1ALDH1A1TP53TSHRCA12 | |
| SCHEMBL3996792 | 0.79 | TP53 (0.47) | EPHX1ALDH1A1TP53TSHRCA12 | |
| SCHEMBL22749453 | 0.78 | DPP4 (0.45) | EPHX1 | |
| SCHEMBL15820587 | 0.77 | EPHX1 (0.41) | EPHX1ALDH1A1TP53 | |
| SCHEMBL14045008 | 0.77 | THRB (0.46) | EPHX1ALDH1A1TP53TSHRCA12 | |
| SCHEMBL11117724 | 0.76 | EPHX1 (0.39) | EPHX1ALDH1A1TP53 | |
| SCHEMBL12071026 | 0.76 | EPHX1 (0.44) | EPHX1DHODHTP53CA12CA1 | |
| SCHEMBL8277386 | 0.76 | EPHX1 (0.44) | EPHX1DHODHTP53CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299342-B1 | METHOD FOR PRODUCING 3,3-DIARYLPROPYLAMINES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-05-02 | — | — | EP | claimed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | claimed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | claimed |
| US-6809225-B2 | BY HYDROCARBONYLATION/HYDROFORMYLATION WITH SUBSEQUENT REDUCTIVE AMINATION | SCHWARZ PHARMA AG (DE) | 2004-10-26 | — | — | US | disclosed |
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | UCB PHARMA GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034080-A1 | Method for producing 3,3-diarylpropylamines | HNMT, CYP1A1, HRH3 | EPHX1 880/4885DHODH 186/4885ALDH1A1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.