Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL517352

C=CC(=O)C(=C)C(=O)C=C.N.N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.39
TSHR P16473 4/20 0.39
FGFR4 P22455 1/20 0.39
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702582 0.96 LMNA (0.44) LMNAALDH1A1TSHRFGFR4TP53
SCHEMBL727397 0.80
SCHEMBL8094858 0.80 LMNA (0.37) LMNAALDH1A1TSHRFGFR4TP53
SCHEMBL403345 0.78
SCHEMBL1825536 0.78
SCHEMBL9356506 0.78
SCHEMBL2751659 0.76
SCHEMBL28994050 0.76 CA4 (0.37) LMNAALDH1A1TSHRFGFR4
SCHEMBL30353586 0.72 ALDH1A1 (0.35) LMNAALDH1A1TSHRTP53
SCHEMBL28414098 0.72 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2110 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116950-A1 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES AND SCAFFOLDS THEREOF FOR USE IN IMMUNOTHERAPY AGAINST COLORECTAL CARCINOMA (CRC) AND OTHER CANCERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2026-04-30 US disclosed
US-20260116918-A1 NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2026-04-30 US disclosed
US-20260028387-A1 PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST ESOPHAGEAL CANCER AND OTHER CANCERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2026-01-29 US disclosed
US-20250235519-A1 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST PANCREATIC CANCER AND OTHER CANCERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-07-24 US disclosed
US-20250223335-A1 PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPY AGAINST HEAD AND NECK SQUAMOUS CELL CARCINOMA AND OTHER CANCERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-07-10 US disclosed
US-12351616-B2 Peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-07-08 US disclosed
WO-2025136809-A2 FOXP3 PEPTIDES AND USES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2025-06-26 WO disclosed
US-12318407-B2 Peptides displayed by HLA for use in immunotherapy against different types of cancers IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-06-03 US disclosed
US-20250154459-A1 PEPTIDES AND COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPY AGAINST RENAL CELL CARCINOMA (RCC) AND OTHER CANCERS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-05-15 US disclosed
US-12297245-B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers IMMATICS BIOTECHNOLOGIES GMBH (DE) 2025-05-13 US disclosed
EP-0284406-B1 Biologically active molecules PITMAN MOORE LTD (GB) 1994-09-14 EP disclosed
WO-1993020213-A1 NISINS AGRICULTURE AND FOOD RESEARCH COUNCIL (GB) 1993-10-14 WO disclosed
WO-1993014209-A1 VACCINES BASED ON STREPTOKINASE SMITHKLINE BEECHAM CORPORATION (US) 1993-07-22 WO disclosed
WO-1993007872-A1 LYSOSOMAL ENZYME INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES THE UNIVERSITY OF NOTTINGHAM (GB) 1993-04-29 WO disclosed
EP-0405763-A1 GRF peptides MALLINCKRODT VETERINARY LIMITED (GB) 1991-01-02 EP disclosed
WO-1990015073-A1 GRF PEPTIDES COOPERS ANIMAL HEALTH LIMITED (GB) 1990-12-13 WO disclosed
WO-1989009226-A1 PEPTIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-10-05 WO disclosed
EP-0335662-A1 Peptides BTG INTERNATIONAL LIMITED (GB) 1989-10-04 EP disclosed
WO-1988007547-A1 BIOLOCICALLY ACTIVE MOLECULES COOPERS ANIMAL HEALTH LIMITED (GB) 1988-10-06 WO disclosed
EP-0284406-A1 Biologically active molecules PITMAN-MOORE LIMITED (GB) 1988-09-28 EP disclosed