SCHEMBL8094858

SCHEMBL8094858

C=CC(=C)C(=C)C(=O)C=C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
FGFR4 P22455 1/20 0.35
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5702582 0.83 LMNA (0.44) LMNAALDH1A1TSHRFGFR4TP53
SCHEMBL27561219 0.80
Ammonia Solution, Strong SCHEMBL517352 0.80 LMNA (0.41) LMNAALDH1A1TSHRFGFR4TP53
SCHEMBL21232219 0.75 ALDH1A1 (0.40) LMNAALDH1A1TSHRTP53
SCHEMBL27428626 0.75 ALDH1A1 (0.40) LMNAALDH1A1TSHRTP53
SCHEMBL727397 0.75
SCHEMBL27621007 0.75
SCHEMBL1825536 0.73
SCHEMBL2051021 0.73 LMNA (0.42) LMNAALDH1A1TSHRFGFR4
SCHEMBL403345 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6111054-A IMPROVEMENT IN DISPERSION AND STABILISATION OF PIGMENTS OR EXTENDER PARTICLES IN BINDER VEHICLES, PIGMENT PASTES OR PLASTICS FORMULATIONS IS ACHIEVED BY USING ADDITIVES PRODUCED BY SALT FORMATION FROM POLYAMINES WITH ORGANIC ACIDS BYK-CHEMIE GMBH (DE) 2000-08-29 US disclosed