Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946154 | 0.87 | PHGDH (0.59) | HPGDALDH1A1L3MBTL3L3MBTL1KMT2A | |
| SCHEMBL9946153 | 0.83 | HPGD (0.55) | HPGDALDH1A1GAAMBTD1L3MBTL3 | |
| SCHEMBL1238180 | 0.82 | ALDH1A1 (0.40) | HPGDALDH1A1GAAL3MBTL3L3MBTL1 | |
| SCHEMBL1235917 | 0.82 | ALDH1A1 (0.40) | HPGDALDH1A1GAAL3MBTL3L3MBTL1 | |
| SCHEMBL517510 | 0.79 | HPGD (0.59) | HPGDALDH1A1MAOAGAAMBTD1 | |
| SCHEMBL517372 | 0.78 | HPGD (0.56) | HPGDALDH1A1MAOAGAAMBTD1 | |
| SCHEMBL27479149 | 0.77 | HPGD (1.00) | HPGDALDH1A1MAOAMBTD1L3MBTL3 | |
| SCHEMBL7132525 | 0.77 | HPGD (1.00) | HPGDALDH1A1MAOAMBTD1L3MBTL3 | |
| SCHEMBL10721733 | 0.75 | HPGD (0.95) | HPGDALDH1A1MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL9946140 | 0.74 | SMN1; SMN2 (0.41) | HPGDALDH1A1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | HPGD 2142/4885ALDH1A1 4010/4885MAOA 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.