Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18076338 | 0.95 | TPSAB1 (0.47) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL10618435 | 0.91 | CTSS (0.40) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL10829472 | 0.89 | ITGB3 (0.45) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL6555710 | 0.88 | NPSR1 (0.40) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL11564615 | 0.88 | NPSR1 (0.40) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL9321962 | 0.88 | ATM (0.45) | TPSAB1TPSD1TPSG1ITGA4ITGB7 | |
| SCHEMBL11651226 | 0.88 | ATM (0.45) | TPSAB1TPSD1TPSG1ITGA4ITGB7 | |
| SCHEMBL8392929 | 0.88 | ATM (0.45) | TPSAB1TPSD1TPSG1ITGA4ITGB7 | |
| SCHEMBL22804079 | 0.87 | ALDH1A1 (0.46) | ITGB3ITGA2BLMNACTSSCTSK | |
| SCHEMBL22804098 | 0.87 | ALDH1A1 (0.46) | ITGB3ITGA2BLMNACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | Receptos, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016015014-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2016-01-28 | — | — | WO | disclosed |