Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174181 | 1.00 | MAPT (0.52) | MAPTPDK1TSHRCASP6PDE7A | |
| SCHEMBL7043142 | 0.87 | CASP6 (0.64) | PDK1TSHRCASP6HCAR3LMNA | |
| SCHEMBL7043138 | 0.87 | CASP6 (0.64) | PDK1TSHRCASP6HCAR3LMNA | |
| SCHEMBL25492001 | 0.84 | PDK1 (0.70) | MAPTPDK1TSHRCASP6PDE7A | |
| SCHEMBL7681987 | 0.82 | MAPK1 (0.62) | MAPTPDK1CASP6MAPK1POLB | |
| SCHEMBL7681995 | 0.82 | MAPK1 (0.62) | MAPTPDK1CASP6MAPK1POLB | |
| SCHEMBL4819821 | 0.81 | KMT2A (0.50) | MAPTPDK1TSHRPDE7APOLB | |
| SCHEMBL27838069 | 0.81 | TSHR (0.55) | PDK1TSHRALDH1A1 | |
| SCHEMBL3582033 | 0.81 | SRD5A2 (0.55) | MAPTPDK1CASP6MAPK1POLB | |
| SCHEMBL3582037 | 0.81 | SRD5A2 (0.55) | MAPTPDK1CASP6MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1785426-A1 | NOVEL CARBAPENEM COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1612211-A1 | NOVEL CARBAPENEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265242-A1 | Novel Carbapenem Compound | C1R, C3AR1, OXA1L | MAPT 4855/4885PDK1 523/4885TSHR 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.