Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183442 | 0.77 | CHRNA7 (0.31) | CHRNA7 | |
| SCHEMBL5174337 | 0.73 | CHRNA1 (0.31) | CHRNA7 | |
| SCHEMBL5173137 | 0.73 | CHRNB2 (0.42) | CHRNA7 | |
| SCHEMBL5173067 | 0.70 | CHRNB2 (0.40) | CHRNA7 | |
| SCHEMBL5173279 | 0.69 | CHRNB2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5174223 | 0.66 | CHRNB2 (0.40) | CHRNA7 | |
| SCHEMBL5173984 | 0.65 | CHRNA3 (0.42) | — | |
| SCHEMBL5183872 | 0.65 | — | — | |
| SCHEMBL5174771 | 0.65 | CHRM2 (0.32) | — | |
| SCHEMBL3463373 | 0.65 | SMYD3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784184-A2 | THE USE OF N-ARYL DIAZASPIRACYCLIC COMPOUNDS IN THE TREATMENT OF ADDICTION | Targacept, Inc. (US) | 2007-05-16 | — | — | EP | claimed |
| WO-2006023630-A2 | THE USE OF N-ARYL DIAZASPIRACYCLIC COMPOUNDS IN THE TREATMENT OF ADDICTION | TARGACEPT, INC. (US) | 2006-03-02 | — | — | WO | claimed |