Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20815 | 0.84 | THRB (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL4630934 | 0.81 | TSHR (0.46) | ALDH1A1TSHRTHRB | |
| SCHEMBL16641681 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL3748063 | 0.76 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL2404913 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL28295079 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL2404914 | 0.75 | TSHR (0.47) | ALDH1A1TSHRTHRB | |
| SCHEMBL27787388 | 0.75 | TSHR (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL28329174 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTHRB | |
| SCHEMBL33644 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789821-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO., Ltd. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006026474-A2 | SILICONE HYDROGEL CONTACT LENSES | ASAHIKASEI AIME CO. LTD. (JP) | 2006-03-09 | — | — | WO | disclosed |