Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 12/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6213630 | 0.99 | ADRA1A (0.54) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL5176069 | 0.88 | HTR1A (0.55) | ADRA1AADRA1BADRA1DCYP3A4DRD2 | |
| Hydrochloric Acid SCHEMBL6407537 | 0.87 | HTR1A (0.55) | ADRA1AADRA1BADRA1DCYP3A4DRD2 | |
| SCHEMBL6212178 | 0.87 | ADRA1A (0.56) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL4528941 | 0.86 | DRD2 (0.64) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL4520908 | 0.85 | DRD2 (0.63) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL4522586 | 0.84 | HTR1A (0.51) | ADRA1AADRA1BADRA1DCYP3A4DRD2 | |
| Hydrochloric Acid SCHEMBL6406164 | 0.84 | ADRA1A (0.57) | ADRA1AADRA1BADRA1DCYP3A4CYP2C9 | |
| SCHEMBL6211445 | 0.83 | DRD2 (0.52) | ADRA1AADRA1BADRA1DCYP3A4DRD2 | |
| Hydrochloric Acid SCHEMBL4517673 | 0.83 | HTR1A (0.51) | DRD2HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746998-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES, LTD. (IN) | 2007-01-31 | — | — | EP | claimed |
| WO-2005092341-A1 | COMBINATION THERAPY FOR LOWER URINARY TRACT SYMPTOMS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-06 | — | — | WO | claimed |
| EP-1495000-A4 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LAB LTD (IN) | 2005-10-05 | — | — | EP | disclosed |
| EP-1495000-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084928-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE Α1Α ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-16 | — | — | WO | disclosed |