Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830419 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BITGAVLTA4H | |
| SCHEMBL7363344 | 0.85 | ITGB3 (0.63) | ITGB3ITGA2BITGAV | |
| SCHEMBL8177199 | 0.84 | ITGB3 (0.69) | ITGB3ITGA2BLTA4HPTPN1 | |
| SCHEMBL8336016 | 0.84 | ITGB3 (0.59) | ITGB3ITGA2B | |
| SCHEMBL5175122 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL30149863 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BITGAV | |
| SCHEMBL6287557 | 0.84 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL7412163 | 0.83 | SIRT2 (0.49) | ITGB3ITGA2BLTA4H | |
| SCHEMBL8341037 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL19485480 | 0.83 | CTSK (0.62) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820991-B1 | Cycloalkyl derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-0907637-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| EP-0820991-A2 | Cycloalkyl derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-28 | — | — | EP | disclosed |
| WO-1998000395-A1 | PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 1998-01-08 | — | — | WO | disclosed |