Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.63 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341037 | 0.97 | ITGB3 (0.60) | ITGB3ITGA2BITGAVHDAC8POLB | |
| SCHEMBL25320494 | 0.88 | HDAC8 (0.58) | ITGB3ITGA2BHDAC8ALDH1A1ALOX15 | |
| SCHEMBL30149863 | 0.88 | ITGB3 (0.67) | ITGB3ITGA2BITGAVPOLBMAPT | |
| SCHEMBL8337850 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2BITGAVHDAC8ALDH1A1 | |
| SCHEMBL9219338 | 0.87 | CTSK (0.62) | ITGB3ITGA2BALDH1A1ALOX15POLB | |
| SCHEMBL19485480 | 0.87 | CTSK (0.62) | ITGB3ITGA2BALDH1A1ALOX15POLB | |
| SCHEMBL8336016 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BHDAC8ALDH1A1 | |
| SCHEMBL5175372 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL8770345 | 0.85 | ITGB3 (0.69) | ITGB3ITGA2BITGAVHDAC8ALDH1A1 | |
| SCHEMBL29260893 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BITGAVALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |