Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128164 | 0.90 | PSEN1 (0.39) | CNR2USP2MAPTNPSR1FNTA | |
| SCHEMBL5122199 | 0.89 | PSEN1 (0.40) | CNR2USP2MAPTNPSR1FNTA | |
| SCHEMBL5176805 | 0.85 | FNTA (0.39) | ACP3MAPTNPSR1FNTAFNTB | |
| SCHEMBL5113412 | 0.85 | SCN8A (0.38) | CNR2CNR1PPARGUSP2MAPT | |
| SCHEMBL5236529 | 0.85 | AVPR2 (0.40) | CNR2PPARAFNTAFNTB | |
| SCHEMBL5175072 | 0.84 | CNR2 (0.42) | CNR2CNR1PPARGUSP2MAPT | |
| SCHEMBL5113431 | 0.84 | MAPT (0.41) | CNR2PPARGUSP2MAPTNPSR1 | |
| SCHEMBL5121770 | 0.84 | TRPM8 (0.39) | CNR1USP2MAPTNPSR1FNTA | |
| SCHEMBL5177320 | 0.84 | FLT1 (0.40) | CNR1NPSR1FNTAFNTBCA1 | |
| SCHEMBL5176207 | 0.82 | PPARG (0.44) | CNR2ACP3PPARGUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747195-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Incorporated (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2005095334-A1 | SULFONAMIDE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS INC. (US) | 2005-10-13 | — | — | WO | claimed |