Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121770 | 0.93 | TRPM8 (0.39) | MAPTUSP2NPSR1TP53POLB | |
| SCHEMBL5186687 | 0.89 | S1PR3 (0.39) | MAPTNPSR1TP53S1PR3S1PR1 | |
| SCHEMBL5186681 | 0.89 | S1PR3 (0.39) | MAPTNPSR1TP53S1PR3S1PR1 | |
| SCHEMBL5176207 | 0.86 | PPARG (0.44) | MAPTUSP2NPSR1FLT1FLT4 | |
| SCHEMBL5175072 | 0.85 | CNR2 (0.42) | MAPTUSP2NPSR1POLBFLT1 | |
| SCHEMBL5128164 | 0.85 | PSEN1 (0.39) | MAPTUSP2NPSR1TP53POLB | |
| SCHEMBL5175656 | 0.85 | CNR2 (0.44) | MAPTUSP2NPSR1FLT1FLT4 | |
| SCHEMBL5122199 | 0.84 | PSEN1 (0.40) | MAPTUSP2NPSR1FLT1FLT4 | |
| SCHEMBL5177184 | 0.84 | EPHX1 (0.39) | CNR1CNR2FNTAFNTBCCR2 | |
| SCHEMBL5186094 | 0.84 | SLC6A9 (0.40) | MAPTFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345095-B2 | Sulfonamide compounds for the treatment of neurodegenerative disorders | PFIZER INC (US) | 2008-03-18 | — | — | US | disclosed |