SCHEMBL5175667

SCHEMBL5175667

CC=CC(=O)N(C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
MITF O75030 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 2/20 0.44
TRPM8 Q7Z2W7 2/20 0.43
FAAH O00519 1/20 0.42
PHGDH O43175 1/20 0.42
MGLL Q99685 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CHRNB2 P17787 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175660 1.00 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175922 0.84 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175912 0.84 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL4022487 0.84 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL1185399 0.83 KMT2A (0.47) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5176493 0.82 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175903 0.82 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175916 0.82 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL21593639 0.81 TRPM8 (0.68) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL20976894 0.81 LMNA (0.47) LMNAMITFALDH1A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3268000-B1 PYRAZOLO[1,5-A][1,3,5]TRIAZINE AND PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS CDK INHIBITORS AURIGENE DISCOVERY TECH LTD (IN) 2021-08-04 EP claimed
WO-2023227125-A1 NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF 杭州德睿智药科技有限公司 2023-11-30 WO disclosed
CN-108349956-A PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS 赛尔维他股份公司 2018-07-31 CN disclosed
CN-104761482-A 3-(2,2-dimethyl) propionitrile-3-alkyl (aryl) indolone and preparation method thereof UNIV JISHOU 2015-07-08 CN disclosed
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-20030129520-A1 Using graft polymer on etched or anodized aluminum substrate FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed