SCHEMBL4022487

SCHEMBL4022487

CN(C(=O)/C=C/C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
MITF O75030 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
KDM4E B2RXH2 1/20 0.44
TRPM8 Q7Z2W7 2/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
FAAH O00519 1/20 0.42
PHGDH O43175 1/20 0.42
MGLL Q99685 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
NR4A1 P22736 1/20 0.42
HDAC3 O15379 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175922 1.00 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175912 1.00 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5176493 0.86 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175903 0.86 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175916 0.86 LMNA (0.48) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175667 0.84 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL5175660 0.84 LMNA (0.49) LMNAMITFALDH1A1MAPTNPC1
SCHEMBL1164367 0.83 HSD17B1 (0.49) LMNAALDH1A1MAPTNPC1RAB9A
SCHEMBL12172748 0.81 KDM4E (0.48) ALDH1A1MAPTNPC1RAB9AKMT2A
Maleic Acid SCHEMBL28501255 0.81 NR4A1 (0.59) LMNAALDH1A1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-7482379-B2 Propenoyl hydrazides GEORGIA TECH RESEARCH CORPORATION (US) 2009-01-27 US disclosed
EP-1602481-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-05-30 EP disclosed
EP-1203659-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-05-17 EP disclosed
EP-1602481-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-12-07 EP disclosed
US-20050256058-A1 Propenoyl hydrazides NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-11-17 US disclosed
EP-1371500-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2005-09-28 EP disclosed
US-6939658-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2005-09-06 US disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6824946-B2 SUPPORT WITH HYDROPHILIC SURFACE HAVING AN IMAGE-FORMING LAYER CONTAINING A HYDROPHOBIC HIGH MOLECULAR COMPOUND WITH SALTS OF SULFONATES AND CARBOXYLS WITH IODONIUM, SULFONIUM OR DIAZONIUM IONS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-6680161-B2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-01-20 US disclosed
EP-1371500-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-12-17 EP disclosed
US-20030190553-A1 Support with hydrophilic surface; multilayer; latex layer and ink receiver FUJIFILM CORPORATION (JP) 2003-10-09 US disclosed
US-6509132-B1 Comprises an ink-receptive image area for receiving ink during the printing process and a hydrophilic non-image area for receiving fountain solution FUJI PHOTO FILM CO., LTD. (JP) 2003-01-21 US disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
US-20020068241-A1 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2002-06-06 US disclosed
EP-1203659-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-05-08 EP disclosed
EP-1136281-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1031414-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS LMNA 2499/4885MITF 4146/4885ALDH1A1 263/4885
US-20050256058-A1 Propenoyl hydrazides DNPEP, HPN, PREP LMNA 2599/4885MITF 3227/4885ALDH1A1 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.