SCHEMBL5176089

SCHEMBL5176089

NC(=O)CCC(NC(N)=O)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
DPP4 P27487 1/20 0.38
DPP8 Q6V1X1 1/20 0.38
DPP9 Q86TI2 1/20 0.38
CA2 P00918 5/20 0.37
CA1 P00915 4/20 0.37
BMP1 P13497 1/20 0.36
NOD1 Q9Y239 1/20 0.36
CAD P27708 1/20 0.35
MMP2 P08253 3/20 0.35
MMP9 P14780 2/20 0.35
HPGDS O60760 1/20 0.35
FOLH1 Q04609 1/20 0.34
RIMKLA Q8IXN7 1/20 0.34
NAALAD2 Q9Y3Q0 1/20 0.34
PTPN1 P18031 1/20 0.33
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19579782 1.00 KMT2A (0.41) KMT2AALOX15BLMPMP22DPP4
SCHEMBL5493511 0.84 KMT2A (0.53) KMT2AALOX15BLMPMP22CA2
SCHEMBL5493512 0.84 KMT2A (0.53) KMT2AALOX15BLMPMP22CA2
SCHEMBL7043592 0.84 KMT2A (0.53) KMT2AALOX15BLMPMP22CA2
SCHEMBL24158322 0.83 SIRT5 (0.43) KMT2AALOX15BLMPMP22DPP4
SCHEMBL7231529 0.81 NOD1 (0.39) KMT2AALOX15BLMPMP22DPP4
SCHEMBL13363671 0.81 NOD1 (0.46) KMT2AALOX15BLMPMP22DPP4
SCHEMBL7231523 0.81 NOD1 (0.39) KMT2AALOX15BLMPMP22DPP4
SCHEMBL13837807 0.79 DPP4 (0.45) KMT2AALOX15BLMPMP22DPP4
SCHEMBL2242130 0.79 DPP4 (0.57) KMT2AALOX15BLMPMP22DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1343907-B1 METHOD FOR THE CONTINUOUS BIOTECHNOLOGICAL PRODUCTION OF COMPATIBLE SOLUTES FROM TOXIC SUBSTRATES HELMHOLTZ ZENT UMWELTFORSCHUNG (DE) 2007-05-30 EP disclosed
EP-1343907-A1 METHOD FOR THE CONTINUOUS BIOTECHNOLOGICAL PRODUCTION OF COMPATIBLE SOLUTES FROM TOXIC SUBSTRATES UFZ-UMWELTFORSCHUNGSZENTRUM LEIPZIG-HALLE GMBH (DE) 2003-09-17 EP disclosed
WO-2002050298-A1 METHOD FOR THE CONTINUOUS BIOTECHNOLOGICAL PRODUCTION OF COMPATIBLE SOLUTES FROM TOXIC SUBSTRATES UFZ-UMWELTFORSCHUNGSZENTRUM LEIPZIG-HALLE GMBH (DE) 2002-06-27 WO disclosed