SCHEMBL5493511

SCHEMBL5493511

NC(=O)CC[C@@H](NC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
FOLH1 Q04609 6/20 0.52
RIMKLA Q8IXN7 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.52
CA2 P00918 5/20 0.50
CA1 P00915 4/20 0.50
ALOX15 P16050 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
MMP2 P08253 2/20 0.44
MMP9 P14780 2/20 0.44
TGFBR1 P36897 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7043592 1.00 KMT2A (0.53) KMT2AFOLH1RIMKLANAALAD2CA2
SCHEMBL5493512 1.00 KMT2A (0.53) KMT2AFOLH1RIMKLANAALAD2CA2
Carglumic Acid SCHEMBL27983953 0.87 FOLH1 (0.69) FOLH1RIMKLANAALAD2CA2CA1
SCHEMBL28282404 0.87 KMT2A (0.53) KMT2AFOLH1RIMKLANAALAD2CA2
Carglumic Acid SCHEMBL27983952 0.87 FOLH1 (0.69) FOLH1RIMKLANAALAD2CA2CA1
SCHEMBL1719073 0.87 KMT2A (0.53) KMT2AFOLH1RIMKLANAALAD2CA2
Carglumic Acid SCHEMBL910483 0.87 FOLH1 (0.69) FOLH1RIMKLANAALAD2CA2CA1
Carglumic Acid SCHEMBL910527 0.87 FOLH1 (0.69) FOLH1RIMKLANAALAD2CA2CA1
Carglumic Acid SCHEMBL373546 0.87 FOLH1 (0.69) FOLH1RIMKLANAALAD2CA2CA1
SCHEMBL7047615 0.85 GNPAT (0.56) KMT2AFOLH1RIMKLANAALAD2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1376202-A Stereostructure of decarbamylase and use thereof KANEGAFUCHI CHEMICAL IND (JP) 2002-10-23 CN claimed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP claimed
EP-1616945-B1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI CHEMICAL IND (JP) 2007-11-21 EP disclosed
EP-0801131-B1 PROCESS FOR PRODUCING D-N-CARBAMOYL-ALPHA-AMINO ACID KANEGAFUCHI CHEMICAL IND (JP) 2007-02-21 EP disclosed
EP-1616945-A1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-01-18 EP disclosed
EP-1616946-A1 Process for producing D-N-carbamoyl-alpha-amino acids KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-01-18 EP disclosed
CN-1376202-A Stereostructure of decarbamylase and use thereof KANEGAFUCHI CHEMICAL IND (JP) 2002-10-23 CN disclosed
EP-1209234-A1 STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME Kaneka Corporation (JP) 2002-05-29 EP disclosed
EP-0801131-A1 PROCESS FOR PRODUCING D-N-CARBAMOYL-$g(a)-AMINO ACID Kanegafuchi Chemical Industry Co., Ltd. (JP) 1997-10-15 EP disclosed