Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 6/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180029 | 1.00 | DNM1 (0.52) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL19032425 | 0.93 | GNAO1 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL19032418 | 0.93 | GNAO1 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL20589546 | 0.93 | GNAI3 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL20589918 | 0.93 | GNAO1 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL19032546 | 0.93 | GNAO1 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL20588862 | 0.93 | GNAI3 (0.47) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL19032420 | 0.91 | GNAO1 (0.45) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL15781599 | 0.90 | GNAO1 (0.46) | DNM1GNAO1GNAI3GNAI1DGKA | |
| SCHEMBL19032516 | 0.89 | GNAO1 (0.48) | DNM1GNAO1GNAI3GNAI1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927174-B1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MEDIGENE AG (DE) | 2007-12-12 | — | — | EP | disclosed |
| EP-0927174-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | MediGene Oncology GmbH (DE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011082-A1 | NEW AMINO ALCOHOL DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND MEDICAMENTS AND REAGENTS CONTAINING THESE COMPOUNDS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-03-19 | — | — | WO | disclosed |