Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517977 | 0.84 | CYP3A4 (0.33) | — | |
| SCHEMBL518053 | 0.82 | POLB (0.34) | EGFRMAPTHTTTSHR | |
| SCHEMBL517581 | 0.80 | POLB (0.33) | TSHR | |
| SCHEMBL11673485 | 0.79 | — | — | |
| SCHEMBL518216 | 0.79 | TSHR (0.31) | TSHR | |
| SCHEMBL518217 | 0.71 | POLB (0.44) | HTTTSHR | |
| SCHEMBL24357851 | 0.69 | LMNA (0.38) | EGFRMAPTHTTTSHR | |
| SCHEMBL10022793 | 0.68 | MAPT (0.44) | EGFRMAPTHTTTSHR | |
| SCHEMBL3373620 | 0.68 | MAPT (0.44) | EGFRMAPTHTTTSHR | |
| SCHEMBL2008228 | 0.67 | NPSR1 (0.41) | EGFRMAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | BROMINE COMPOUNDS LTD. (IL) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | PIK3CA, PIP5K1B, PIP5K1C | EGFR 1316/4885MAPT 3971/4885HTT 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.