Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674659 | 0.77 | LMNA (0.33) | POLBNPSR1LMNAHPGDMEN1 | |
| SCHEMBL5506535 | 0.77 | CA1 (0.41) | POLBNPSR1NR1I2KCNH2ACHE | |
| SCHEMBL517581 | 0.77 | POLB (0.33) | POLBNPSR1KCNH2LMNAGAA | |
| SCHEMBL518054 | 0.75 | POLB (0.38) | POLBNPSR1KDM4ELMNAHPGD | |
| SCHEMBL518053 | 0.73 | POLB (0.34) | POLBNPSR1NR1I2GAATSHR | |
| SCHEMBL643902 | 0.73 | ALDH1A1 (0.40) | POLBNPSR1NR1I2KCNH2ACHE | |
| SCHEMBL13337650 | 0.72 | NPSR1 (0.48) | POLBNPSR1NR1I2KCNH2ACHE | |
| SCHEMBL517780 | 0.71 | EGFR (0.34) | TSHRHTT | |
| SCHEMBL9614639 | 0.71 | TSHR (0.48) | POLBNPSR1KCNH2ACHETSHR | |
| SCHEMBL3146731 | 0.71 | TSHR (0.48) | POLBNPSR1KCNH2ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | BROMINE COMPOUNDS LTD. (IL) | 2012-02-02 | — | — | US | disclosed |
| WO-2010046899-A2 | IMPROVED FLAME RETARDATION OF TEXTILES BY HALOGENATED ARYL PHOSPHONATES | BROMINE COMPOUNDS LTD. (IL) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029224-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED ARYL PHOSPHONATES | PIK3CA, PIP5K1B, PIP5K1C | POLB 1353/4885NPSR1 3576/4885NR1I2 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.