SCHEMBL51781

SCHEMBL51781

CCC(c1ccccc1)C1CO1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.44
CHRM4 P08173 2/20 0.44
CHRM5 P08912 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.40
TAAR1 Q96RJ0 2/20 0.40
CYP2D6 P10635 1/20 0.40
PKM P14618 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51979 0.85 CHRM2 (0.42) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28384720 0.82 CHRM2 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28146857 0.80 CHRM2 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL6939077 0.79 OPRM1 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL27265070 0.79 OPRM1 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL18129993 0.79 ALDH1A1 (0.42) TSHR
SCHEMBL6941362 0.79 OPRM1 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28226318 0.77 TRPA1 (0.41) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11181290 0.77 SLC6A2 (0.56) CHRM2CHRM1CHRM3CYP2D6
SCHEMBL27259892 0.76 CYP2C19 (0.43) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104448451-A Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD 2015-03-25 CN claimed
CN-109535707-B Pneumatic tire 横滨橡胶株式会社 2021-05-25 CN disclosed
EP-2508342-B1 INNER LINER FOR PNEUMATIC TIRE, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-04-01 EP disclosed
EP-2508343-B1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-03-11 EP disclosed
EP-2554372-B1 MULTILAYERED STRUCTURE AND LAMINATE AND METHOD FOR PRODUCTION OF THE SAME KURARAY CO (JP) 2020-01-08 EP disclosed
EP-2857451-B1 PNEUMATIC TIRE YOKOHAMA RUBBER CO LTD (JP) 2019-05-08 EP disclosed
CN-107116869-B Multilayer structure making, pneumatic tire inner liner and pneumatic tire 株式会社普利司通 2019-04-30 CN disclosed
EP-2623315-B1 MULTILAYERED STRUCTURE, INNER LINER HAVING THE SAME, AND PNEUMATIC TIRE KURARAY CO (JP) 2019-04-17 EP disclosed
EP-2716445-B1 MULTI-LAYERED STRUCTURE, INNER LINER FOR PNEUMATIC TIRE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2019-04-10 EP disclosed
CN-109535707-A Pneumatic tire 横滨橡胶株式会社 2019-03-29 CN disclosed
CN-101010362-A Multilayered pellet comprising ethylene/vinyl alcohol copolymer resin compositions KURARAY CO (JP) 2007-08-01 CN disclosed
EP-1785446-A1 MULTILAYERED PELLET COMPRISING ETHYLENE/VINYL ALCOHOL COPOLYMER RESIN COMPOSITIONS KURARAY CO., LTD. (JP) 2007-05-16 EP disclosed
CN-1294198-C Resin composition and multi-layer structures KURARAY CO (JP) 2007-01-10 CN disclosed
CN-1231501-C Modified ethylene-vinyl alcohol copolymer and method for producing same KURARAY CO (JP) 2005-12-14 CN disclosed
CN-1649956-A Resin composition and multi-layer structures KURARAY CO (JP) 2005-08-03 CN disclosed
US-20050147778-A1 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2005-07-07 US disclosed
EP-1479725-A1 RESIN COMPOSITION AND MULTI-LAYER STRUCTURES Kuraray Co., Ltd. (JP) 2004-11-24 EP disclosed
US-20040096683-A1 Modified ethylene-vinyl alcohol copolymer and method for the production thereof KURARAY CO., LTD. (JP) 2004-05-20 US disclosed
EP-1403289-A1 MODIFIED ETHYLENE−VINYL ALCOHOL COPOLYMER AND METHOD FOR THE PRODUCTION THEREOF Kuraray Co., Ltd. (JP) 2004-03-31 EP disclosed
CN-1464883-A Modified ethylene-vinyl alcohol copolymer and method for producing same KURARAY CO (JP) 2003-12-31 CN disclosed