Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093075 | 0.93 | HIF1A (0.44) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL1044726 | 0.88 | — | — | |
| SCHEMBL12056719 | 0.83 | HIF1A (0.56) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL4120017 | 0.79 | HIF1A (0.53) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL13043858 | 0.79 | HIF1A (0.53) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL1238019 | 0.79 | TP53 (0.50) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL4131499 | 0.75 | TP53 (0.58) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL4135092 | 0.70 | TP53 (0.69) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL7887806 | 0.70 | HIF1A (0.47) | HIF1ATP53MAPTTHRBCYP3A4 | |
| SCHEMBL1238217 | 0.70 | CYP1A2 (0.42) | HIF1ATP53MAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| EP-3368542-B1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2018-09-27 | — | — | US | disclosed |
| EP-1069104-B1 | PROCESS FOR PRODUCING HINOKITIOL | ASAHI CHEMICAL IND (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-6310255-B1 | Process for producing hinokitiol | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1069104-A1 | PROCESS FOR PRODUCING HINOKITIOL | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-0631474-B1 | CYCLIC ANTI-TUMOR PROMOTER COMPOUNDS, COMPOSITIONS AND METHODS FOR PRODUCTION AND USE | UNIV HAWAII (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032587-A1 | METHODS FOR TREATING VIRAL INFECTIONS | DANA-FARBER CANCER INSTITUTE (US) | 1997-09-12 | — | — | WO | disclosed |
| EP-0631474-A4 | CYCLIC ANTI-TUMOR PROMOTER COMPOUNDS, COMPOSITIONS AND METHODS FOR PRODUCTION AND USE. | — | 1995-01-25 | — | — | EP | disclosed |
| EP-0631474-A1 | CYCLIC ANTI-TUMOR PROMOTER COMPOUNDS, COMPOSITIONS AND METHODS FOR PRODUCTION AND USE | UNIVERSITY OF HAWAII (US) | 1995-01-04 | — | — | EP | disclosed |
| US-5349112-A | Cyclic anti-tumor promoter compounds, compositions and methods for production and use | UNIVERSITY OF HAWAII (US) | 1994-09-20 | — | — | US | disclosed |
| US-5276217-A | Anticarcinogenic, analog of sarcophytol A, carbocyclic compound with 6-14 ring carbons | UNIVERSITY OF HAWAII (US) | 1994-01-04 | — | — | US | disclosed |
| WO-1993018651-A1 | CYCLIC ANTI-TUMOR PROMOTER COMPOUNDS, COMPOSITIONS AND METHODS FOR PRODUCTION AND USE | UNIVERSITY OF HAWAII (US) | 1993-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | HIF1A 2575/4885TP53 4492/4885MAPT 4340/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | HIF1A 2571/4885TP53 4412/4885MAPT 1377/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | HIF1A 2575/4885TP53 4492/4885MAPT 4340/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | HIF1A 3487/4885TP53 3839/4885MAPT 1637/4885 |
| US-20180273517-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | HIF1A 3487/4885TP53 3839/4885MAPT 1637/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | HIF1A 2575/4885TP53 4492/4885MAPT 4340/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | HIF1A 2575/4885TP53 4492/4885MAPT 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.