SCHEMBL5178458

SCHEMBL5178458

N#CCSc1ccccc1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
SMN1; SMN2 Q16637 6/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 2/20 0.39
ALDH1A1 P00352 5/20 0.38
RAB9A P51151 2/20 0.37
HTT P42858 1/20 0.37
HPGD P15428 4/20 0.36
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
EGFR P00533 1/20 0.36
FYN P06241 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7699313 0.79 DBH (0.37) CA12CA2CA14SMN1; SMN2LMNA
SCHEMBL11346446 0.77 MEN1 (0.52) CA12CA2CA14CA1CA9
SCHEMBL8746041 0.76 EPHX2 (0.42) ALDH1A1RAB9AHPGDKDM4ENPC1
Cyanate SCHEMBL7108613 0.76 P4HB (0.42) CA12CA2CA14SMN1; SMN2LMNA
SCHEMBL15916767 0.75 HTR7 (0.47) CA12CA2CA14CA1CA9
SCHEMBL17376519 0.75 LMNA (0.39) CA12CA2CA14CA1CA9
SCHEMBL17041429 0.75 LMNA (0.39) CA12CA2CA14CA1CA9
SCHEMBL8397211 0.75 LMNA (0.45) CA12CA2CA14CA1CA9
SCHEMBL68951 0.75 HSPA5 (0.46) CA12CA2CA14SMN1; SMN2LMNA
SCHEMBL9361652 0.73 TDP1 (0.37) CA12CA2CA14CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938677-A4 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN INC (US) 2000-09-27 EP claimed
EP-0938677-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1999-09-01 EP claimed
US-5843666-A Chemiluminescent detection methods using dual enzyer-labeled binding partners LUMIGEN, INC. (US) 1998-12-01 US claimed
WO-1998021586-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1998-05-22 WO claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
EP-1015641-B1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2007-06-13 EP disclosed
EP-1015641-A4 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN INC (US) 2003-04-16 EP disclosed
EP-0938677-A4 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN INC (US) 2000-09-27 EP disclosed
EP-1015641-A1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 2000-07-05 EP disclosed
US-6068979-A IMMOBILIZING TARGETS, CONTACTING WITH LABELED SPECIFIC BINDING PARTNERS FOR EACH TARGET, REACTING WITH SUBSTRATE FOR FIRST LABEL, DETECTING, REACTING WITH SUBSTRATE FOR SECOND ENZYME, DETECTING; ELIMINATES NEED FOR STRIPPING/REPROBING LUMIGEN, INC. (US) 2000-05-30 US disclosed
WO-1999054503-A1 SIMPLIFIED SEQUENTIAL CHEMILUMINESCENT DETECTION LUMIGEN, INC. (US) 1999-10-28 WO disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed
EP-0267582-A2 2-Chloro-4-( (Cyanomethyl)thio)phenyl N-methyl carbamate MERRELL DOW PHARMACEUTICALS INC. (US) 1988-05-18 EP disclosed