Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11845425 | 0.98 | LMNA (0.46) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Acetic Acid Methyl Ester SCHEMBL28854245 | 0.88 | MEN1 (0.51) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Acetone SCHEMBL4283217 | 0.87 | GAA (0.54) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Sulfuric Acid SCHEMBL528133 | 0.87 | GAA (0.59) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Sulfuric Acid SCHEMBL526314 | 0.87 | GAA (0.59) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Acetone SCHEMBL2978474 | 0.85 | GAA (0.52) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Acetic Acid SCHEMBL443433 | 0.85 | SMN1; SMN2 (0.52) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Sulfuric Acid SCHEMBL5581686 | 0.85 | GAA (0.56) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| Sulfuric Acid SCHEMBL15544394 | 0.85 | GAA (0.56) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL34 | 0.85 | GAA (0.62) | LMNAALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116173313-A | Preparation method of medical surgical membrane material with self-antibacterial function | 合肥科天水性科技有限责任公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112322254-B | Biomass aldehyde-free adhesive and preparation and application methods thereof | 南宁科天水性科技有限责任公司 | 2022-04-08 | — | — | CN | claimed |
| CN-112322254-A | Biomass aldehyde-free adhesive and preparation and application methods thereof | 合肥科天水性科技有限责任公司 | 2021-02-05 | — | — | CN | claimed |
| CN-109646793-B | Transurethral prostate expanding catheter and expanding method thereof | 江苏长寿棒科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-116337984-A | Method for quantitatively detecting hydroxyl value of hydroxyl-terminated polybutadiene compound | 青岛科技大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116173313-A | Preparation method of medical surgical membrane material with self-antibacterial function | 合肥科天水性科技有限责任公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-112322254-B | Biomass aldehyde-free adhesive and preparation and application methods thereof | 南宁科天水性科技有限责任公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-109925589-B | Novel prostate expands and splits pipe | 江苏长寿棒科技有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-112322254-A | Biomass aldehyde-free adhesive and preparation and application methods thereof | 合肥科天水性科技有限责任公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-1270071-B1 | Ion-exchange membrane | TOKUYAMA CORP (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-7012041-B2 | Phenylpyridazinones | BAYER AG (DE) | 2006-03-14 | — | — | US | disclosed |
| US-6830671-B2 | A polyether compound having polyalkylene glycol chain is fixed on the surface of the membrane and/or inside of the membrane. | TOKUYAMA CORPORATION (JP) | 2004-12-14 | — | — | US | disclosed |
| US-20030119673-A1 | Phenylpyridazinones | LINKER KARL-HEINZ (DE) | 2003-06-26 | — | — | US | disclosed |
| US-6551963-B1 | For controlling unwanted vegetation | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| US-20030024816-A1 | Ion-exchange membrane | TOKUYAMA CORPORATION (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1270071-A1 | Ion-exchange membrane | TOKUYAMA CORPORATION (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6268395-B1 | FOR EXAMPLE ANTI-HIV AGENT; HAVING HIGHER ANTIVIRAL EFFECTS AND LESS DELETERIOUS SIDE EFFECTS AS COMPARED WITH CONVENTIONALLY KNOWN ANTIVIRAL AGENTS. | LEAD CHEMICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-4554289-A | OF4949 | TAKARA SHUZO CO., LTD. (JP) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119673-A1 | Phenylpyridazinones | CYP2D6, CYP1A1, CYP1B1 | LMNA 4189/4885ALDH1A1 35/4885MAPT 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.