Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexanoate SCHEMBL27322791 | 1.00 | FFAR4 (0.59) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Adipic Acid SCHEMBL28148639 | 0.90 | FFAR4 (0.49) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Adipic Acid SCHEMBL11345301 | 0.89 | FFAR4 (0.48) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Stearic Acid SCHEMBL27546902 | 0.88 | FFAR4 (0.66) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Adipic Acid SCHEMBL630307 | 0.88 | FFAR4 (0.74) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Hexanoate SCHEMBL10616908 | 0.88 | AKR1B1 (0.70) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Hexanoate SCHEMBL9654616 | 0.88 | AKR1B1 (0.70) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Phthalic Acid SCHEMBL5178755 | 0.87 | ALDH1A1 (0.47) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL736748 | 0.86 | FFAR4 (0.48) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| Azelaic Acid SCHEMBL11247067 | 0.86 | GPR84 (0.71) | FFAR4FFAR1AKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659333-A | Water-based polyurethane and preparation method and application thereof | 上海华峰新材料研发科技有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-113929850-B | Aqueous polyurethane sizing agent and preparation method and application thereof | 上海华峰新材料研发科技有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-109651582-B | Waterborne polyurethane ink binder and preparation method thereof | 上海华峰新材料研发科技有限公司 | 2022-02-01 | — | — | CN | claimed |
| EP-1027381-B2 | WATERBORNE POLYURETHANE HAVING FILM PROPERTIES COMPARABLE TO RUBBER | NOVEON INC (US) | 2007-10-31 | — | — | EP | claimed |
| EP-1027381-B1 | WATERBORNE POLYURETHANE HAVING FILM PROPERTIES COMPARABLE TO RUBBER | NOVEON IP HOLDINGS CORP (US) | 2002-03-20 | — | — | EP | claimed |
| EP-1027381-A1 | WATERBORNE POLYURETHANE HAVING FILM PROPERTIES COMPARABLE TO RUBBER | The B.F. Goodrich Company (US) | 2000-08-16 | — | — | EP | claimed |
| US-6017997-A | THE ELASTOMERIC POLYURETHANE COPOLYMERS IS THE REACTION PRODUCT OF A POLYISOCYANATES AND A POLYAMIDE, A POLYESTER POLYOL, A POLYETHER POLYOL AND MIXTURES THEREOF; THE FORMED FILM HAVING HIGH TENSILE STRENGTH, ELONGATION, STRETCHING | THE B. F. GOODRICH COMPANY (US) | 2000-01-25 | — | — | US | claimed |
| WO-1999023129-A1 | WATERBORNE POLYURETHANE HAVING FILM PROPERTIES COMPARABLE TO RUBBER | THE B.F. GOODRICH COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| US-4346201-A | COATINGS FOR FLEXIBLE SUBSTRATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-24 | — | — | US | claimed |
| US-11952505-B1 | One component self-crosslinking coatings | SWIMC LLC (US) | 2024-04-09 | — | — | US | disclosed |
| EP-4340807-A1 | HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS | Lubrizol Advanced Materials, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117659333-A | Water-based polyurethane and preparation method and application thereof | 上海华峰新材料研发科技有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117355290-A | Hair coloring composition for reducing color loss | 路博润先进材料公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230416653-A1 | ANTIMICROBIAL CLEANING COMPOSITIONS CONTAINING POLYURETHANE SALTED WITH BIS-BIGUANIDE FREE BASE | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2023-12-28 | — | — | US | disclosed |
| EP-0126297-A1 | Method for adhering two different surfaces by means of water dispersible polyurethane adhesive compostitions | NL Spencer Kellogg, Inc. (US) | 1984-11-28 | — | — | EP | disclosed |
| US-4331717-A | NEUTRALIZATION OF TERTIARY NITROGEN ATOMS WITH ORGANIC ACID, CORROSION RESISTANCE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |
| US-4293657-A | Stable melamine polyol dispersions, a process for their manufacture and for the preparation of foamed polyurethane plastics | BASF AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4223147-A | POLYMER STABILIZERS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |
| US-4197219-A | Aqueous polyurethane-phenolic-formaldehyde resin emulsions for use as adhesives, primers and surface coatings | LORD CORPORATION (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153596-A | PHOTOSTABILITY | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | disclosed |