Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690094 | 0.86 | NPC1 (0.48) | NPC1RAB9AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL9450739 | 0.86 | NPC1 (0.48) | NPC1RAB9AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL4000024 | 0.79 | CHRM1 (0.50) | NPC1RAB9AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL14690050 | 0.76 | MAPT (0.51) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL6418936 | 0.76 | NPC1 (0.59) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL217821 | 0.76 | ATIC (0.39) | ALDH1A1TDP1HPGDGAAMAPT | |
| SCHEMBL9702645 | 0.75 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL1813599 | 0.74 | NPC1 (0.46) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL397783 | 0.74 | KMT2A (0.47) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL14431063 | 0.73 | JAK3 (0.36) | NPC1RAB9AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208974-B1 | Processless lithographic printing plate | AGFA GRAPHICS NV (BE) | 2007-06-13 | — | — | EP | disclosed |
| EP-1266750-B1 | Method for preparation of a lithographic printing plate | AGFA GEVAERT (BE) | 2005-06-08 | — | — | EP | disclosed |
| US-6790595-B2 | BASE WITH A HYDROPHILIC SURFACE, AN OLEOPHILIC IMAGING LAYER AND A CROSS-LINKED HYDROPHILIC UPPER LAYER OF SULFONIC ACID, SULFURIC ACID, PHOSPHORIC ACID OR PHOSPHONIC ACID DERIVATIVES | AGFA-GEVAERT (BE) | 2004-09-14 | — | — | US | disclosed |
| US-6772687-B2 | Method for the preparation of a lithographic printing plate | AGFA-GEVAERT (BE) | 2004-08-10 | — | — | US | disclosed |
| US-20030089259-A1 | Method for the preparation of a lithographic printing plate | AGFA GRAPHICS NV (BE) | 2003-05-15 | — | — | US | disclosed |
| EP-1266750-A1 | Method for preparation of a lithographic printing plate | Agfa-Gevaert (BE) | 2002-12-18 | — | — | EP | disclosed |
| US-20020068239-A1 | Processless lithographic printing plate | AGFA-GEVAERT (BE) | 2002-06-06 | — | — | US | disclosed |
| EP-1208974-A2 | Processless lithographic printing plate | Agfa-Gevaert (BE) | 2002-05-29 | — | — | EP | disclosed |