SCHEMBL217821

SCHEMBL217821

C=C(C)C(=O)Nc1ccccc1N=Nc1ccc(S(=O)(=O)O)c(O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATIC P31939 1/20 0.39
▸ ENPP2 Q13822 1/20 0.39
▸ GLO1 Q04760 2/20 0.37
▸ CYP1A2 P05177 3/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA3 P07451 1/20 0.37
▸ SENP2 Q9HC62 4/20 0.36
▸ SENP1 Q9P0U3 4/20 0.36
▸ SUMO2 P61956 3/20 0.36
▸ SUMO1 P63165 3/20 0.36
▸ SENP7 Q9BQF6 3/20 0.36
▸ CTRB1 P17538 1/20 0.36
▸ SENP3 Q9H4L4 3/20 0.36
▸ PRMT3 O60678 1/20 0.36
▸ EP300 Q09472 1/20 0.36
▸ PRMT6 Q96LA8 1/20 0.36
▸ PRMT1 Q99873 1/20 0.36
▸ MEN1 O00255 3/20 0.35
▸ MAPT P10636 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219154 0.82 KMT2A (0.46) GLO1CYP1A2ALDH1A1MEN1MAPT
SCHEMBL4651722 0.82 KMT2A (0.46) GLO1CYP1A2ALDH1A1MEN1MAPT
SCHEMBL218264 0.79 MEN1 (0.41) CYP1A2ALDH1A1MEN1MAPTKMT2A
SCHEMBL9450739 0.79 NPC1 (0.48) ALDH1A1MAPTHPGDALOX12RECQL
SCHEMBL14690094 0.79 NPC1 (0.48) ALDH1A1MAPTHPGDALOX12RECQL
SCHEMBL4000024 0.78 CHRM1 (0.50) ALDH1A1SENP7MEN1MAPTKMT2A
SCHEMBL14690050 0.77 MAPT (0.51) ALDH1A1MEN1MAPTKMT2ATHRB
SCHEMBL4651757 0.77 CA12 (0.43) CYP1A2ALDH1A1CA2SENP7MEN1
SCHEMBL217397 0.77 CA12 (0.43) CYP1A2ALDH1A1CA2SENP7MEN1
SCHEMBL5178845 0.76 NPC1 (0.40) ALDH1A1MAPTHPGDRECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 — — US disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 — — EP disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 — — WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 — — US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 — — US disclosed
EP-1466214-A2 NEGATIVE-WORKING PHOTOIMABEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2004-10-13 — — EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 — — US disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 ATIC 3700/4885ENPP2 2406/4885GLO1 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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