Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ATIC | P31939 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.47 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.45 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.45 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27204585 | 0.76 | POLB (0.55) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL9614749 | 0.75 | ENPP2 (0.53) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL10897349 | 0.75 | CYP1A2 (0.59) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL8594512 | 0.75 | CD40 (0.54) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL8594508 | 0.75 | CD40 (0.54) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL10424165 | 0.75 | ALDH1A1 (0.54) | CYP2C9HSD17B10CYP2C19CYP1A2PTPRC | |
| SCHEMBL31255636 | 0.75 | ALDH1A1 (0.54) | CYP2C9HSD17B10CYP2C19CYP1A2PTPRC | |
| SCHEMBL10812260 | 0.75 | NT5E (0.60) | CYP2C9HSD17B10CYP2C19CYP1A2PTPN11 | |
| SCHEMBL14418343 | 0.74 | CYP1A2 (0.85) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC | |
| SCHEMBL112146 | 0.74 | CYP1A2 (0.85) | CYP2C9HSD17B10CYP2C19CYP1A2ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047390-B1 | DUAL COMPONENT ANTIPLAQUE DENTIFRICE COMPOSITION | COLGATE PALMOLIVE CO (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1553918-A1 | DUAL COMPONENT BIS-BIGUANIDE CONTAINING DENTIFRICE OF IMPROVED STABILITY | Colgate-Palmolive Company (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004054530-A1 | METHOD FOR OPTIMIZING FLUORIDE UPTAKE OF TEETH BY APPLYING A LIQUID DENTIFRICE COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20040115140-A1 | Liquid dentifrice compositions of optimized fluoride uptake | COLGATE-PALMOLIVE COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1428518-A2 | Method for optimizing fluoride uptake of teeth by applying a liquid dentifrice composition | Colgate-Palmolive Company (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1406578-A1 | CATIONIC ANTIBACTERIAL DENTIFRICE EXHIBITING SUPERIOR FOAMING PROPERTIES | Colgate-Palmolive Company (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2004010963-A1 | DUAL COMPONENT BIS-BIGUANIDE CONTAINING DENTIFRICE OF IMPROVED STABILITY | COLGATE-PALMOLIVE COMPANY (US) | 2004-02-05 | — | — | WO | disclosed |
| US-6613310-B1 | First component is an extrudable gel containing: vehicle, cellulose polymer thickener, and antibacterial agent; the second component is an extrudable paste containing a silica abrasive; being physically separated from each until dispensed | COLGATE PALMOLIVE COMPANY | 2003-09-02 | — | — | US | disclosed |
| WO-2002089755-A1 | CATIONIC ANTIBACTERIAL DENTIFRICE EXHIBITING SUPERIOR FOAMING PROPERTIES | COLGATE-PALMOLIVE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |
| US-6447758-B1 | COMBINING CATIONIC ANTIBACTERIAL AGENT AND ANIONIC SURFACTANT WHEN APPLYING TO TEETH; SUPERIOR FOAMING PROPERTIES | COLGATE PALMOLIVE COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1061893-B1 | BIS-BIGUANIDE DENTIFRICE EXHIBITING REDUCED STAINING | COLGATE PALMOLIVE CO (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1119342-A1 | DUAL COMPONENT ANTIPLAQUE AND TOOTH WHITENING COMPOSITION | Colgate-Palmolive Company (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-1061893-A1 | BIS-BIGUANIDE ANTIPLAQUE DENTIFRICE EXHIBITING REDUCED STAINING | Colgate-Palmolive Company (US) | 2000-12-27 | — | — | EP | disclosed |
| US-6110446-A | DENTIFRICE WITH ABRASIVE, NONIONIC SURFACTANT AND BACETERICIDE | COLGATE PALMOLIVE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |
| US-6106812-A | PEROXIDE IN VEHICLE THICKENED WITH WATER INSOLUBLE PARTICLES AND NON-ALKYLENE OXIDE THICKENER; DENTIFRICES | COLGATE-PALMOLIVE COMPANY | 2000-08-22 | — | — | US | disclosed |
| WO-2000019971-A1 | DUAL COMPONENT ANTIPLAQUE AND TOOTH WHITENING COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |
| US-5958381-A | DENTAL COMPOSITION IN WHICH FIRST COMPONENT IS EXTRUDABLE GEL CONTAINING BIS-BIGUANIDE ANTIBACTERIAL AGENT, SECOND COMPONENT IS EXTRUDABLE PASTE CONTAINING INCOMPATIBLE ABRASIVE, BEING SYNCHRONOUSLY EXTRUDABLE FOR APPLICATION TO TEETH | COLGATE PALMOLIVE COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1999045898-A1 | BIS-BIGUANIDE ANTIPLAQUE DENTIFRICE EXHIBITING REDUCED STAINING | COLGATE-PALMOLIVE COMPANY (US) | 1999-09-16 | — | — | WO | disclosed |
| US-5843406-A | Dual components antiplaque dentifrice compositions | COLGATE PALMOLIVE COMPANY (US) | 1998-12-01 | — | — | US | disclosed |