SCHEMBL112146

SCHEMBL112146

O=S(=O)(O)c1ccc(/N=N/c2c(O)ccc3cc(S(=O)(=O)O)ccc23)cc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 3/20 0.85
▸ CYP2C9 P11712 2/20 0.85
▸ THRB P10828 2/20 0.73
▸ HIF1A Q16665 3/20 0.65
▸ TSHR P16473 1/20 0.65
▸ PTPRA P18433 1/20 0.65
▸ PTPRB P23467 1/20 0.65
▸ CYP2C19 P33261 1/20 0.65
▸ RAPGEF4 Q8WZA2 1/20 0.65
▸ HSD17B10 Q99714 1/20 0.65
▸ KMT2A Q03164 4/20 0.62
▸ MAPT P10636 3/20 0.62
▸ TDP1 Q9NUW8 3/20 0.62
▸ GAA P10253 2/20 0.62
▸ MAPK1 P28482 1/20 0.62
▸ MEN1 O00255 3/20 0.59
▸ SENP7 Q9BQF6 2/20 0.54
▸ SUMO2 P61956 1/20 0.54
▸ SUMO1 P63165 1/20 0.54
▸ SENP2 Q9HC62 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142459 1.00 CYP1A2 (0.85) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL628908 1.00 CYP1A2 (0.85) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL30940027 1.00 CYP1A2 (0.85) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL14418343 1.00 CYP1A2 (0.85) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL30486026 0.99 CYP1A2 (0.83) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL4808250 0.99 CYP1A2 (0.83) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL28291310 0.99 CYP1A2 (0.83) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL142457 0.99 CYP1A2 (0.83) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL14413302 0.96 CYP2C9 (0.79) CYP1A2CYP2C9THRBHIF1ATSHR
SCHEMBL5321833 0.94 CYP2C9 (0.81) CYP1A2CYP2C9THRBHIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 602 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727287-B1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM OREAL (FR) 2024-12-04 — — EP claimed
EP-2543706-B1 METHOD FOR STABILIZING OF COLOR DEVELOPER AND USE THEREOF ARKRAY INC (JP) 2021-05-26 — — EP claimed
EP-3727287-A1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM L'OREAL (FR) 2020-10-28 — — EP claimed
WO-2018115451-A1 COSMETIC COMPOSITION FOR DIRECT DYEING COMPRISING AN AQUEOUS PHASE AND A FATTY PHASE THAT ARE VISUALLY DISTINCT FROM EACH OTHER L'OREAL (FR) 2018-06-28 — — WO claimed
WO-2018115450-A1 PROCESS FOR DIRECT DYEING OF KERATIN FIBRES COMPRISING THE APPLICATION OF TWO PARTICULAR COMPOSITIONS L'OREAL (FR) 2018-06-28 — — WO claimed
EP-3001190-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, Inc. (JP) 2016-03-30 — — EP claimed
EP-2543706-A2 Stabilizer of color former and use thereof ARKRAY, Inc. (JP) 2013-01-09 — — EP claimed
US-8273577-B2 Method for detecting phenothiazine-derivative color and color-developer reagent used therein ARKRAY, INC. (JP) 2012-09-25 — — US claimed
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF ARKRAY, INC. (JP) 2011-01-20 — — US claimed
EP-2270105-A1 STABILIZER FOR COLOR DEVELOPER AND USE THEREOF ARKRAY, Inc. (JP) 2011-01-05 — — EP claimed
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, INC. (JP) 2010-05-06 — — US claimed
EP-2108952-A1 METHOD FOR DETECTION OF PHENOTHIAZINE DERIVATIVE DYE, AND COLOR-DEVELOPER REAGENT FOR USE IN THE METHOD Arkray, Inc. (JP) 2009-10-14 — — EP claimed
EP-0252278-B1 Disinfecting agents and their use in disinfecting the skin and mucous membranes HENKEL KGAA (DE) 1998-08-19 — — EP claimed
EP-0252278-A2 Disinfecting agents and their use in disinfecting the skin and mucous membranes Henkel Kommanditgesellschaft auf Aktien (DE) 1988-01-13 — — EP claimed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 — — US claimed
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition L'OREAL (FR) 2026-01-27 — — US disclosed
US-20250381106-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2025-12-18 — — US disclosed
US-4560746-A MONOAZO DYES, 2-(2-QUINOLYL)-1,3-INDANEDIONESULFONIC ACID THE HILTON-DAVIS CHEMICAL CO. (US) 1985-12-24 — — US disclosed
US-4459277-A Plaque disclosing dentifrice compositions with solid microcapsules of dye KOSTI CARL M 1984-07-10 — — US disclosed
US-4348378-A Plaque disclosing dentifrice compositions with semi-solid microcapsules of dye KOSTI CARL M 1982-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition KRT18, CA12, CA7 CYP1A2 1655/4885CYP2C9 1221/4885THRB 2468/4885
US-20250381106-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, MAP1LC3A CYP1A2 1319/4885CYP2C9 2571/4885THRB 4386/4885
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN TH, TYR, HPD CYP1A2 85/4885CYP2C9 68/4885THRB 1943/4885
US-20110015391-A1 STABILIZER OF COLOR FORMER AND USE THEREOF TYR, CRYZ, MITF CYP1A2 850/4885CYP2C9 2181/4885THRB 4885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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