Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22192224 | 0.90 | MAPT (0.64) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL5180990 | 0.90 | MAPT (0.64) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL9695914 | 0.89 | MAPT (0.73) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL7294717 | 0.89 | MAPT (0.73) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL7302201 | 0.86 | NPC1 (0.74) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL8770602 | 0.85 | GAA (0.64) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL7291792 | 0.85 | NR1H4 (0.69) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL8742834 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL7302398 | 0.83 | SMN1; SMN2 (0.72) | TRPV1HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL22192232 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |