Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181396 | 1.00 | ALDH1A1 (0.37) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL5180922 | 0.87 | CRHBP (0.34) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL5180767 | 0.83 | KDM4E (0.34) | GAAKDM4ESMN1; SMN2 | |
| SCHEMBL4179681 | 0.79 | KDM4E (0.39) | ALDH1A1GAALMNAL3MBTL1MAPT | |
| SCHEMBL29198655 | 0.79 | KMT2A (0.46) | ALDH1A1GAAKMT2AMEN1LMNA | |
| Resomelagon SCHEMBL23716726 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMEN1LMNA | |
| Resomelagon SCHEMBL30084728 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMEN1LMNA | |
| Resomelagon SCHEMBL12123680 | 0.77 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL4176725 | 0.77 | KMT2A (0.41) | ALDH1A1GAAKMT2AMEN1LMNA | |
| Resomelagon SCHEMBL30064309 | 0.76 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | claimed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | claimed |
| EP-1414440-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | Melacure Therapeutics AB (SE) | 2004-05-06 | — | — | EP | claimed |
| WO-2003013509-A1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTION LIGANDS | MELACURE THERAPEUTICS AB (SE) | 2003-02-20 | — | — | WO | claimed |
| EP-1414440-B1 | N-PHENYLPYRROLE GUANIDINE DERIVATIVES AS MELANOCORTIN RECEPTOR LIGANDS | ACTION PHARMA AS (DK) | 2007-01-10 | — | — | EP | disclosed |
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | ACTION PHARMA A/S (DK) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148798-A1 | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | MC1R, MC5R, MC3R | ALDH1A1 3755/4885GAA 3366/4885KMT2A 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.