SCHEMBL5181981

SCHEMBL5181981

CS(=O)(=O)N[C@@H]1CCCCC1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.40
CA2 P00918 3/20 0.40
CA12 O43570 3/20 0.40
MMP2 P08253 2/20 0.40
MMP9 P14780 2/20 0.40
CA9 Q16790 2/20 0.40
MMP1 P03956 1/20 0.40
MMP3 P08254 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
THRB P10828 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.36
ANPEP P15144 1/20 0.36
ERAP2 Q6P179 1/20 0.36
HCRTR2 O43614 7/20 0.34
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
KAT2B Q92831 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5182563 1.00 CA1 (0.40) CA1CA2CA12MMP2MMP9
SCHEMBL5181970 1.00 CA1 (0.40) CA1CA2CA12MMP2MMP9
SCHEMBL5182557 1.00 CA1 (0.40) CA1CA2CA12MMP2MMP9
SCHEMBL809996 1.00 CA1 (0.40) CA1CA2CA12MMP2MMP9
Benzene SCHEMBL5179558 0.92 ALDH1A1 (0.36) CA1CA2CA12MMP2MMP9
Benzene SCHEMBL5179367 0.92 ALDH1A1 (0.36) CA1CA2CA12MMP2MMP9
Hexamethylbenzene SCHEMBL5418276 0.91 LMNA (0.35) CA1CA2CA12MMP2MMP9
Hexamethylbenzene SCHEMBL5418228 0.91 LMNA (0.35) CA1CA2CA12MMP2MMP9
SCHEMBL5422332 0.86 SYK (0.41) ALDH1A1
P-Xylene SCHEMBL5424714 0.86 ALDH1A1 (0.44) HCRTR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1439159-B1 Process for producing optically active compound KANTO KAGAKU (JP) 2007-06-20 EP disclosed
EP-1439159-A1 Process for producing optically active compound Kanto Kagaku Kabushiki Kaisha (JP) 2004-07-21 EP disclosed