Benzene

Benzene

SCHEMBL5179367

CS(=O)(=O)N[C@H]1CCCC[C@@H]1N.[Ru].c1ccccc1

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MMP2 P08253 3/20 0.36
MMP9 P14780 3/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MMP13 P45452 2/20 0.36
MMP1 P03956 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
HCRTR2 O43614 4/20 0.36
KAT2B Q92831 1/20 0.35
MCOLN2 Q8IZK6 1/20 0.34
MCOLN1 Q9GZU1 1/20 0.34
GRIA4 P48058 2/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL5179558 1.00 ALDH1A1 (0.36) ALDH1A1NPSR1MMP2MMP9CA12
SCHEMBL809996 0.92 CA1 (0.40) ALDH1A1MMP2MMP9CA12CA1
SCHEMBL5182563 0.92 CA1 (0.40) ALDH1A1MMP2MMP9CA12CA1
SCHEMBL5181981 0.92 CA1 (0.40) ALDH1A1MMP2MMP9CA12CA1
SCHEMBL5182557 0.92 CA1 (0.40) ALDH1A1MMP2MMP9CA12CA1
SCHEMBL5181970 0.92 CA1 (0.40) ALDH1A1MMP2MMP9CA12CA1
Toluene SCHEMBL5416727 0.89 ALDH1A1 (0.40) ALDH1A1NPSR1MMP2MMP9MMP13
Toluene SCHEMBL5415721 0.89 ALDH1A1 (0.40) ALDH1A1NPSR1MMP2MMP9MMP13
Hexamethylbenzene SCHEMBL5418276 0.87 LMNA (0.35) ALDH1A1MMP2MMP9CA12CA1
Hexamethylbenzene SCHEMBL5418228 0.87 LMNA (0.35) ALDH1A1MMP2MMP9CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7268250-B2 Process for producing optically active compound KANTO KAGAKU KABUSHIKI KAISHA (JP) 2007-09-11 US disclosed
EP-1439159-B1 Process for producing optically active compound KANTO KAGAKU (JP) 2007-06-20 EP disclosed
US-20040176616-A1 Process for producing optically active compound KANTO KAGAKU KABUSHIKI KAISHA 2004-09-09 US disclosed
EP-1439159-A1 Process for producing optically active compound Kanto Kagaku Kabushiki Kaisha (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176616-A1 Process for producing optically active compound OSTC, NPEPPS, PPOX ALDH1A1 3566/4885NPSR1 3017/4885MMP2 3386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.