Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893203 | 0.86 | CYP1A2 (0.36) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL5183590 | 0.86 | CYP1A2 (0.36) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL14471548 | 0.84 | TSHR (0.35) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL14471627 | 0.81 | BMP1 (0.33) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL14471620 | 0.79 | SELP (0.34) | CTSK | |
| SCHEMBL19809606 | 0.78 | GABRP (0.35) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL19809608 | 0.78 | GABRP (0.35) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL13007473 | 0.75 | HDAC6 (0.34) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL3966183 | 0.75 | FOLH1 (0.34) | SLC6A2SLC6A4BLMSLC6A3MEN1 | |
| SCHEMBL20089212 | 0.74 | MMP13 (0.36) | SLC6A2SLC6A4BLMSLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673384-A4 | NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2007-02-07 | — | — | EP | disclosed |
| EP-1673384-A2 | NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030135-A2 | NITROSATED GLUTAMIC ACID COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2005-04-07 | — | — | WO | disclosed |