Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | MST1R | Q04912 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407652 | 0.88 | MET (0.52) | METKDRAXLSRCTGFBR1 | |
| SCHEMBL5182026 | 0.83 | MET (0.51) | METKDRMST1R | |
| SCHEMBL3855044 | 0.80 | MET (0.55) | METKDRMST1R | |
| SCHEMBL19689606 | 0.80 | MET (0.55) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL2325654 | 0.79 | MET (0.52) | METKDRSRCTGFBR1 | |
| SCHEMBL19689580 | 0.79 | MET (0.55) | METKDRMST1R | |
| SCHEMBL2200943 | 0.79 | MET (0.53) | METKDRMST1RSRCTGFBR1 | |
| SCHEMBL29693560 | 0.77 | MET (0.52) | METKDRMST1R | |
| SCHEMBL2906698 | 0.76 | MET (0.53) | METKDRAXL | |
| SCHEMBL5054285 | 0.76 | MET (0.57) | METKDRAXLSRCTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054928-A1 | c-Met modulators and methods of use | EXELIXIS, INC. (US) | 2007-03-08 | — | — | US | claimed |
| US-20070054928-A1 | c-Met modulators and methods of use | EXELIXIS, INC. (US) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054928-A1 | c-Met modulators and methods of use | FLT4, FLT1, MET | MET 3/4885KDR 4/4885AXL 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.