Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.52 |
| ▸ | KDR | P35968 | 4/20 | 0.49 |
| ▸ | MST1R | Q04912 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906698 | 0.90 | MET (0.53) | METKDR | |
| SCHEMBL2330038 | 0.90 | MET (0.45) | METKDR | |
| SCHEMBL9987663 | 0.89 | MET (0.56) | MET | |
| SCHEMBL2330029 | 0.89 | MET (0.56) | MET | |
| SCHEMBL3855044 | 0.86 | MET (0.55) | METKDRMST1R | |
| SCHEMBL2200943 | 0.85 | MET (0.53) | METKDRMST1R | |
| SCHEMBL2325654 | 0.83 | MET (0.52) | METKDR | |
| SCHEMBL3832327 | 0.81 | MET (0.54) | METKDR | |
| SCHEMBL2326114 | 0.80 | MET (0.52) | METKDR | |
| SCHEMBL407652 | 0.79 | MET (0.52) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |