Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617678 | 0.87 | ALDH1A1 (0.34) | TSHRPKMALDH1A1MAPK1LMNA | |
| SCHEMBL7810661 | 0.82 | — | — | |
| SCHEMBL7812152 | 0.79 | ALDH1A1 (0.34) | PKMALDH1A1LMNAMAPT | |
| SCHEMBL7804838 | 0.78 | ALDH1A1 (0.33) | PKMALDH1A1LMNAMAPT | |
| SCHEMBL11754477 | 0.78 | MAPT (0.31) | MAPT | |
| SCHEMBL8813561 | 0.78 | GAA (0.42) | ALDH1A1MAPK1MAPTATMKDM4E | |
| SCHEMBL11735982 | 0.77 | GPR84 (0.40) | PKMALDH1A1 | |
| SCHEMBL10398923 | 0.77 | HRH1 (0.36) | ALDH1A1LMNAMAPT | |
| SCHEMBL8411619 | 0.76 | SMN1; SMN2 (0.33) | MAPTKDM4EGAA | |
| SCHEMBL11347719 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | claimed |
| EP-1799698-A1 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | Angiogene Pharmaceuticals Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | disclosed |
| WO-2006032921-A1 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | ANGIOGENE PHARMACEUTICALS LIMITED (GB) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | disclosed |
| WO-2002081466-A1 | PRODRUGS OF 3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES | SUGEN, INC. (US) | 2002-10-17 | — | — | WO | disclosed |
| EP-0006463-A1 | Process for the production of 2-substituted 1-alkyl-nitroimidazoles | BASF Aktiengesellschaft (DE) | 1980-01-09 | — | — | EP | disclosed |