Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804838 | 0.95 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTKCNJ1PKM | |
| SCHEMBL7810661 | 0.90 | — | — | |
| SCHEMBL11735982 | 0.81 | GPR84 (0.40) | ALDH1A1PKM | |
| SCHEMBL10398923 | 0.81 | HRH1 (0.36) | ALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL5182829 | 0.79 | TSHR (0.38) | ALDH1A1LMNAMAPTPKM | |
| SCHEMBL11617678 | 0.77 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTPKM | |
| SCHEMBL8413024 | 0.76 | HASPIN (0.33) | ALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL11754477 | 0.75 | MAPT (0.31) | MAPT | |
| SCHEMBL8813561 | 0.75 | GAA (0.42) | ALDH1A1MAPT | |
| SCHEMBL8413090 | 0.75 | HASPIN (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706523-B1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-01-24 | — | — | EP | disclosed |
| US-5773451-A | BACTERICIDES FOR HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0706523-A1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001351-A1 | SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-01-12 | — | — | WO | disclosed |