Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664606 | 0.81 | LMNA (0.42) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL15808674 | 0.80 | GAA (0.36) | GAATGFBR1CA1CA2CA12 | |
| SCHEMBL15201198 | 0.78 | GAA (0.52) | GAACA1CA2CA12CA9 | |
| SCHEMBL31264254 | 0.77 | GAA (0.45) | LMNACYP2C19BLMGAATGFBR1 | |
| SCHEMBL1404471 | 0.74 | CYP2D6 (0.40) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL28685473 | 0.74 | ALOX15 (0.50) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL33972 | 0.74 | ALOX15 (0.50) | LMNASLC6A6CYP2C19BLMAPP | |
| SCHEMBL41304 | 0.74 | TGFBR1 (0.37) | LMNASLC6A6CYP2C19BLMCYP2D6 | |
| SCHEMBL11693252 | 0.74 | PTGS1 (0.31) | LMNASLC6A6CYP2C19BLMCYP2D6 | |
| SCHEMBL11690410 | 0.74 | PTGS1 (0.31) | LMNASLC6A6CYP2C19BLMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952095-A | Synthetic method of 2-carboxylic acid ethyl ester-5-brooethyl thiazole | SHENGSHI TAIKE BIOLOG MEDICAL TECHNOLOGY SUZHOU CO LTD | 2013-03-06 | — | — | CN | claimed |
| CN-102666552-B | Bicyclic thiazoles as allosteric modulators of the MGLUR5 receptor | JANSSEN PHARMACEUTICA NV | 2014-11-26 | — | — | CN | disclosed |
| CN-104086528-A | Novel heterocyclic compounds as pesticides | BAYER IP GMBH | 2014-10-08 | — | — | CN | disclosed |
| CN-101273042-B | Macrocyclic inhibitors of hepatitis C virus | TIBOTEC PHARM LTD | 2013-11-06 | — | — | CN | disclosed |
| CN-103130792-A | 2-aminothiazoles compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-06-05 | — | — | CN | disclosed |
| CN-103140483-A | novel heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG | 2013-06-05 | — | — | CN | disclosed |
| CN-103130791-A | Novel benzamides compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-06-05 | — | — | CN | disclosed |
| CN-102952095-A | Synthetic method of 2-carboxylic acid ethyl ester-5-brooethyl thiazole | SHENGSHI TAIKE BIOLOG MEDICAL TECHNOLOGY SUZHOU CO LTD | 2013-03-06 | — | — | CN | disclosed |
| CN-102947280-A | Carboxy-oxazole or thiazole compounds as DGAT-1 inhibitors useful for the treatment of obesity | PIRAMAL LIFE SCIENCES LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-101868563-B | Base processing agent for metal material and method for processing base for metal material | NIHON PARKERIZING | 2012-09-12 | — | — | CN | disclosed |
| CN-1355810-A | Prodrugs of thrombin inhibitors | BASF AG (DE) | 2002-06-26 | — | — | CN | disclosed |
| CN-1351593-A | Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants agents | PHARMACIA CO (US) | 2002-05-29 | — | — | CN | disclosed |
| CN-1341592-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341590-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1341593-A | Proteinase inhibitor | SMITHKLINE BEECHEM CORP (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1290263-A | Arylpiperidine derivatives and use thereof | NIHON NOHYAKU CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1289341-A | Thrombin inhibitors | BASF AG (DE) | 2001-03-28 | — | — | CN | disclosed |
| CN-1210531-A | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1999-03-10 | — | — | CN | disclosed |
| CN-1207095-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-02-03 | — | — | CN | disclosed |
| CN-1207102-A | 5h,10h-imidazo[1,2-alpha] indeno [1,2-3] pyrazine-4-one derivatives preparation thereof, intermediates thereof and drugs containing same | RHONE POULENC RORER SA (FR) | 1999-02-03 | — | — | CN | disclosed |