Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.61 |
| ▸ | GNMT | Q14749 | 1/20 | 0.57 |
| ▸ | WDR5 | P61964 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RBBP5 | Q15291 | 4/20 | 0.56 |
| ▸ | DPY30 | Q9C005 | 4/20 | 0.56 |
| ▸ | ASH2L | Q9UBL3 | 4/20 | 0.56 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.55 |
| ▸ | NNMT | P40261 | 5/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.53 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.53 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727574 | 0.91 | MARS1 (0.61) | AHCYDOT1LGNMTWDR5KMT2A | |
| SCHEMBL28127840 | 0.82 | EZH2 (0.65) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL17164713 | 0.82 | EZH2 (0.65) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL19111341 | 0.81 | SMYD3 (0.66) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL14905991 | 0.80 | CARM1 (0.59) | AHCYDOT1LNNMTSETD2TRDMT1 | |
| SCHEMBL622588 | 0.78 | ADORA1 (0.69) | AHCYDOT1LKMT2A | |
| SCHEMBL28939535 | 0.77 | EZH2 (0.59) | AHCYDOT1LWDR5KMT2ARBBP5 | |
| SCHEMBL30532261 | 0.77 | EZH2 (0.63) | DOT1LWDR5KMT2ARBBP5DPY30 | |
| SCHEMBL11420629 | 0.76 | AHCY (0.73) | AHCYDOT1L | |
| SCHEMBL11420645 | 0.76 | AHCY (0.73) | AHCYDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812454-A2 | CHEMICAL SYNTHESIS OF S-ADENOSYL-L-METHIONINE WITH ENRICHMENT OF (S,S)-ISOMER | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006000883-A2 | CHEMICAL SYNTHESIS OF S-ADENOSYL-L-METHIONINE WITH ENRICHMENT OF (S,S)-ISOMER | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2006-01-05 | — | — | WO | disclosed |