SCHEMBL5186197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6561643	0.90	ALDH1A1 (0.39)	KIF11GRIA4NR3C2NR3C1CYP2C19
	SCHEMBL5186063	0.87	RXRA (0.40)	KIF11GRIA4ALDH1A1
	SCHEMBL5187253	0.86	CA12 (0.41)	KIF11GRIA4PTGES2CYP3A4PTPN1
	SCHEMBL5187821	0.86	KIF11 (0.48)	KIF11NR3C2CYP2C19CYP3A4CYP11B1
	SCHEMBL5186196	0.85	KIF11 (0.39)	KIF11GRIA4MMP13PTGES2CYP2C19
	SCHEMBL5186164	0.85	KIF11 (0.50)	KIF11PTGES2
	SCHEMBL5186139	0.85	KIF11 (0.39)	KIF11GRIA4NR3C1CYP2C19ALDH1A1
	SCHEMBL6155949	0.85	KIF11 (0.50)	KIF11PTGES2
	SCHEMBL6155989	0.85	KIF11 (0.50)	KIF11PTGES2
	SCHEMBL5186056	0.84	KIF11 (0.44)	KIF11GRIA4PTPN5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.