Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11343230 | 0.78 | PDGFRB (0.61) | PDGFRBPDGFRALMNACYP2C9NPC1 | |
| SCHEMBL435125 | 0.77 | PDGFRB (0.64) | PDGFRBPDGFRALMNACYP2C9CA2 | |
| SCHEMBL29354931 | 0.77 | PDGFRB (0.64) | PDGFRBPDGFRALMNACYP2C9CA2 | |
| SCHEMBL7913605 | 0.76 | PDGFRB (0.59) | PDGFRBPDGFRALMNACYP2C9NPC1 | |
| SCHEMBL15212564 | 0.75 | CA2 (0.49) | PDGFRALMNACA2CA1CA9 | |
| SCHEMBL1857786 | 0.73 | PDGFRB (0.59) | PDGFRBPDGFRALMNACYP2C9NPC1 | |
| SCHEMBL1575609 | 0.72 | EPHB4 (0.52) | LMNACA2CA1CA9CA12 | |
| SCHEMBL5128693 | 0.72 | CA2 (0.49) | LMNACYP2C9CA2CA1CA9 | |
| SCHEMBL11261266 | 0.71 | ALOX5AP (0.51) | CA2CA1CA9CA12NPC1 | |
| SCHEMBL1385573 | 0.71 | LMNA (0.66) | PDGFRBPDGFRALMNACYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102570-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | Syngenta Participations AG (CH) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015117563-A1 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-13 | — | — | WO | disclosed |
| EP-1802611-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | Syngeta Participations AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040113-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-20 | — | — | WO | disclosed |