Sugi Predict

Sugi Predict / Compounds / SCHEMBL435125

SCHEMBL435125

SCHEMBL435125

NS(=O)(=O)c1ccc(Nc2cnc3ccccc3n2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDGFRB P09619 1/20 0.64
▸ PDGFRA P16234 1/20 0.64
▸ NPC1 O15118 2/20 0.59
▸ RAB9A P51151 2/20 0.59
▸ CDK2 P24941 2/20 0.56
▸ CDK1 P06493 1/20 0.55
▸ CCNB1 P14635 1/20 0.55
▸ CCNA2 P20248 1/20 0.55
▸ CCNE1 P24864 1/20 0.55
▸ CDK5 Q00535 1/20 0.55
▸ CDK5R1 Q15078 1/20 0.55
▸ LMNA P02545 1/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ CA1 P00915 6/20 0.54
▸ CA2 P00918 6/20 0.54
▸ CA9 Q16790 6/20 0.54
▸ CA12 O43570 4/20 0.54
▸ CA6 P23280 1/20 0.54
▸ CA5A P35218 1/20 0.54
▸ CA7 P43166 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29354931 1.00 PDGFRB (0.64) PDGFRBPDGFRANPC1RAB9ACDK2
SCHEMBL7692457 0.87 PDGFRB (0.52) PDGFRBPDGFRANPC1RAB9ACDK2
SCHEMBL29138807 0.85 NPC1 (0.48) PDGFRBPDGFRANPC1RAB9ACDK2
SCHEMBL28771449 0.81 CDK2 (0.55) CDK2CDK1CCNB1CCNA2CCNE1
SCHEMBL9965273 0.81 NPC1 (0.64) NPC1RAB9ACDK2CDK1CCNB1
SCHEMBL8610333 0.79 PDGFRB (1.00) PDGFRBPDGFRANPC1RAB9ACDK2
SCHEMBL5186223 0.77 PDGFRB (0.51) PDGFRBPDGFRANPC1RAB9ALMNA
SCHEMBL27839336 0.76 PDGFRB (0.80) PDGFRBPDGFRANPC1RAB9AMEN1
SCHEMBL6213413 0.76 PDGFRB (0.74) PDGFRBPDGFRANPC1RAB9ALMNA
SCHEMBL1634576 0.75 IKBKB (0.58) CDK2CDK1CCNB1CCNA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1941 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 — — US claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 — — US claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 — — CN claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 — — WO claimed
WO-2020127319-A1 PLANT GROWTH REGULATOR COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-06-25 — — WO claimed
EP-2347655-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngenta Participations AG. (CH) 2011-07-27 — — EP claimed
EP-2332411-A1 Fungicidal compositions Syngenta Participations AG (CH) 2011-06-15 — — EP claimed
JP-2008509189-A — — 2008-03-27 — — JP claimed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 — — US claimed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 — — US claimed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US claimed
EP-1802198-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-07-04 — — EP claimed
EP-1796464-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-06-20 — — EP claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 — — EP claimed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO claimed
WO-2006037632-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006037634-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006037633-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 — — WO claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 PDGFRB 4795/4885PDGFRA 4811/4885NPC1 2315/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX PDGFRB 4182/4885PDGFRA 4529/4885NPC1 2915/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 PDGFRB 4093/4885PDGFRA 4344/4885NPC1 1049/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA PDGFRB 3146/4885PDGFRA 3590/4885NPC1 571/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C PDGFRB 4315/4885PDGFRA 4543/4885NPC1 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.