Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100543 | 0.78 | ENPP3 (0.65) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL4530936 | 0.74 | MGAM (0.49) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1388381 | 0.72 | DYRK1A (0.66) | ADORA2AKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL427925 | 0.72 | MEN1 (0.75) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL13210267 | 0.72 | ENPP3 (0.63) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17144996 | 0.72 | KDM4E (0.65) | PDE4AKDM4EALDH1A1MAPK1MEN1 | |
| SCHEMBL4831635 | 0.71 | CYP1A2 (0.56) | ADORA2AKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15100535 | 0.71 | LTA4H (0.55) | ADORA2AKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3044785 | 0.71 | KMO (0.55) | ADORA2AKDM4EALDH1A1MAPK1MEN1 | |
| Bromide SCHEMBL8360766 | 0.71 | NPC1 (0.73) | KDM4EALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551813-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2007-07-11 | — | — | EP | claimed |
| EP-1551813-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2004032882-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-04-22 | — | — | WO | claimed |