SCHEMBL5186376

SCHEMBL5186376

C=CC(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.65
CYP1A2 P05177 1/20 0.61
HSD17B10 Q99714 1/20 0.61
MAPT P10636 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 2/20 0.54
RAB9A P51151 2/20 0.54
EGFR P00533 1/20 0.54
PABPC1 P11940 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
DNMT1 P26358 1/20 0.50
RAD52 P43351 1/20 0.50
SMARCA2 P51531 1/20 0.50
TERT O14746 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7179864 0.95 MAOA (0.57) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL10934388 0.89 MEN1 (0.50) MAOACYP1A2HSD17B10MAPTMEN1
SCHEMBL11509346 0.84 HSD17B10 (0.47) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL9851275 0.81 MAOA (0.60) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL12296150 0.81 MEN1 (0.64) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL11125302 0.80 CYP1A2 (0.53) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL2601918 0.79 MAOA (1.00) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL12960466 0.78 MAOA (0.69) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL11742788 0.78 MAOA (0.73) MAOACYP1A2HSD17B10MAPTL3MBTL1
SCHEMBL20271919 0.78 MAOA (0.69) MAOACYP1A2HSD17B10MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102702420-B Preparation method of color polyacrylate polymer microspheres UNIV JIANGNAN 2014-05-21 CN disclosed
CN-102702420-A Preparation method of color polyacrylate polymer microspheres UNIV JIANGNAN 2012-10-03 CN disclosed
US-7179308-B2 Ethylenically-unsaturated blue anthraquinone dyes EASTMAN CHEMICAL COMPANY (US) 2007-02-20 US disclosed
US-20070032598-A1 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups CYR MICHAEL J 2007-02-08 US disclosed
US-7172634-B2 Ethylenically-unsaturated blue anthraquinone dyes EASTMAN CHEMICAL COMPANY (US) 2007-02-06 US disclosed
EP-1739135-A2 Colorant compounds containing copolymerizable vinyl groups Eastman Chemical Company (US) 2007-01-03 EP disclosed
US-20060282960-A1 ETHYLENICALLY-UNSATURATED BLUE ANTHRAQUINONE DYES PEARSON JASON C 2006-12-21 US disclosed
EP-1658339-B1 ETHYLENICALLY-UNSATURATED BLUE ANTHRAQUINONE DYES EASTMAN CHEM CO (US) 2006-12-13 EP disclosed
US-7141685-B2 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY (US) 2006-11-28 US disclosed
US-7138539-B2 Colorant compounds containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY (US) 2006-11-21 US disclosed
EP-1304360-A1 Reactive anthraquinone colorant compounds and polymeric materials reacted therewith EASTMAN CHEMICAL COMPANY (US) 2003-04-23 EP disclosed
US-20020132874-A1 Colorant compounds containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY 2002-09-19 US disclosed
US-20020128343-A1 Colorants containing copolymerizable vinyl groups and sulfonamide linkages EASTMAN CHEMICAL COMPANY 2002-09-12 US disclosed
US-20020068725-A1 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups EASTMAN CHEMICAL COMPANY 2002-06-06 US disclosed
WO-2002012402-A2 COLORANT COMPOUNDS CONTAINING COPOLYMERIZABLE VINYL GROUPS EASTMAN CHEMICAL COMPANY (US) 2002-02-14 WO disclosed
WO-2002012403-A2 COLORANTS CONTAINING COPOLYMERIZABLE VINYL GROUPS AND SULFONAMIDE LINKAGES EASTMAN CHEMICAL COMPANY (US) 2002-02-14 WO disclosed
WO-2002012401-A2 THERMALLY STABLE, ANTHRAQUINONE COLORANTS CONTAINING COPOLYMERIZABLE VINYL GROUPS EASTMAN CHEMICAL COMPANY (US) 2002-02-14 WO disclosed
WO-2002012400-A2 THERMALLY STABLE, ANTHRAQUINONE COLORANTS CONTAINING COPOLYMERIZABLE VINYL GROUPS EASTMAN CHEMICAL COMPANY (US) 2002-02-14 WO disclosed
US-5367039-A Anthraquinone dyes, toners, paints, inks, acrylic polymers NIPPON PAINT COMPANY, LTD. (JP) 1994-11-22 US disclosed
US-4101269-A Dyed polymers and copolymers having a cyanovinyl-azo dye incorporated in the structure thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128343-A1 Colorants containing copolymerizable vinyl groups and sulfonamide linkages SMARCD1, SMARCA2, SMARCA4 MAOA 3039/4885CYP1A2 3020/4885HSD17B10 3480/4885
US-20020068725-A1 Thermally stable, anthraquinone colorants containing copolymerizable vinyl groups ALAD, AAAS, ACMSD MAOA 989/4885CYP1A2 1310/4885HSD17B10 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.